Maternal Serum AFP

Maternal Serum AFP

Test Code

5059
82105
CPT Code is subject to a Medicare Limited Coverage Policy and may require a signed ABN when ordering.
5059
82105
CPT Code is subject to a Medicare Limited Coverage Policy and may require a signed ABN when ordering.
Ordering Restrictions may apply. Please provide SERVICE AREA INFORMATION to find available tests you can order.
Not offered in Quest Diagnostics Nichols Institute (IFD) – San Juan Capistrano. Please provide SERVICE AREA INFORMATION to find available tests you can order.
In-home collection is not available in your area through Quest Mobile.

Clinical Significance

Maternal Serum AFP - Maternal serum alpha-fetoprotein (MSAFP) is used for prenatal screening. Maternal serum Alpha-Fetoprotein (AFP) elevation is associated with open neural tube defects, multiple gestation, placental anomalies, ventral abdominal wall defects, congenital nephrosis, and oligohydramnios. Follow-up for abnormal AFP results include genetic counseling, level II or III ultrasound examination and consideration of amniocentesis for chromosome and AFP analysis. MSAFP is not to be used as a screening test for chromosomal abnormalities.

Test Resources

Test FAQ

Maternal Serum AFP

Algorithm

Prenatal Screening and Diagnosis For Open Neural Tube Defects By Measuring AFP

Clinical Focus

Prenatal Screening and Diagnosis of Fetal Chromosomal Abnormalities and Open Neural Tube Defects

Test Details

Includes

  • AFP
    Maternal Risk Interpretation

Methodology

Immunoassay (IA)

Assay Category

This test code is for non-New York patient testing. For New York patient testing, use test code 92788.

Alternative Name(s)

Alpha-Fetoprotein, Maternal Serum,Neural Tube Defect Screen,AFP Single Screen,MSS1

LOINC® Codes, Performing Laboratory

Service Area must be determined
AFP
Maternal Risk Interpretation

Methodology

Immunoassay (IA)
This test code is for non-New York patient testing. For New York patient testing, use test code 92788.

Alternative Name(s)

Alpha-Fetoprotein, Maternal Serum,Neural Tube Defect Screen,AFP Single Screen,MSS1
Service Area must be determined

Preferred Specimen(s)

1 mL serum

Minimum Volume

0.5 mL

Transport Container

Serum separator tube (SST)

Transport Temperature

Room temperature

Specimen Stability

  • Room temperature: 14 days
  • Refrigerated: 14 days
  • Frozen: 45 days

Reject Criteria

Grossly lipemic

Setup Schedule, Collection Instructions

Service Area must be determined
1 mL serum
0.5 mL
Serum separator tube (SST)
Room temperature
Room temperature: 14 days
Refrigerated: 14 days
Frozen: 45 days
Grossly lipemic
Service Area must be determined
Ordering Restrictions may apply. Please provide SERVICE AREA INFORMATION to find available tests you can order.
Not offered in Quest Diagnostics Nichols Institute (IFD) – San Juan Capistrano. Please provide SERVICE AREA INFORMATION to find available tests you can order.
In-home collection is not available in your area through Quest Mobile.
Test Details

Clinical Significance

Test Resources

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

The CPT codes provided are based on AMA guidance and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

This material contains content from LOINC® (http://loinc.org). The LOINC Table, LOINC Table Core are copyright © 1995-2019, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license.

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