Vitamin B₁(Thiamine), Blood, LC/MS/MS

Test code

5042

CPT code(s)*

84425

**CPT Code is subject to a Medicare Limited Coverage Policy and may require a signed ABN when ordering.

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Not offered in Quest Diagnostics Nichols Institute (IFD) – San Juan Capistrano. Please provide Service Area Information to find available tests you can order.

In-home collection may be available in your area for purchase through Quest Mobile.

Clinical significance

Vitamin B₁(Thiamine), Blood, LC/MS/MS - Vitamin B1 is required for branched-chain amino acid and carbohydrate metabolism. Vitamin B1 deficiency is most often due to alcoholism or chronic illness. In the early stage, patients with vitamin B1 deficiency exhibit anorexia, irritability, apathy, and generalized weakness. Prolonged deficiency causes beriberi.

Test resources

Clinical focus

New

Dementia: Biomarkers for Differential Diagnosis and Alzheimer's Disease Assessment

Details

Test details

Methodology

Chromatography/Mass Spectrometry

Assay category

This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Alternative name(s)

Thiamine,B₁

Specimen requirements
Patient preparation	Overnight fasting is required
Preferred specimen(s)	2 mL whole blood collected in an EDTA (lavender-top) tube - protected from light
Alternative specimen(s)	Foil wrapped transport tube protected from light
Minimum volume	1 mL
Collection instructions	Transfer whole blood to amber transport tube. If amber tube is not available, wrap tube in aluminum foil to protect from light. Freeze immediately.
Transport container	Amber transport tube
Transport temperature	Frozen
Specimen stability	Room temperature: 8 hours Refrigerated: 5 days Frozen: 35 days
Reject criteria	Received room temperature and not protected from light • Received refrigerated and not protected from light

Reference range(s)

78-185 nmol/L

LOINC® codes

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Service Area Information

Performing lab & setup schedule

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Service Area Information

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

*The CPT codes provided are based on AMA guidance and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

This material contains content from LOINC® (http://loinc.org). The LOINC Table, LOINC Table Core are copyright © 1995-2019, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license.

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