Hepatitis B Surface Antigen with Reflex Confirmation

Hepatitis B Surface Antigen with Reflex Confirmation

Test Code

498
87340
CPT Code is subject to a Medicare Limited Coverage Policy and may require a signed ABN when ordering.
498
87340
CPT Code is subject to a Medicare Limited Coverage Policy and may require a signed ABN when ordering.
In-home collection may be available in your area for purchase through Quest Mobile.

Clinical Significance

Hepatitis B Surface Antigen with Reflex Confirmation - Surface antigen usually appears in the serum after an incubation period of 1 to 6 months following exposure to Hepatitis B virus and peaks shortly after onset of symptoms. It typically disappears within 1 to 3 months. Persistence of Hepatitis B Surface Antigen for greater than 6 months is a prognostic indicator of chronic Hepatitis B infection.

Test Resources

Test FAQ

Biotin: Interference with Laboratory Assays

Algorithm

Laboratory Testing in the Diagnosis of Hepatitis A, B, or C Virus Infection

Clinical Focus

Viral Hepatitis: Laboratory Support for Diagnosis and Management

Topic Brief

Laboratory Diagnosis of Peripheral Neuropathy

Test Guide

HIV Infection: Laboratory Testing for Diagnosis and Management

Test Details

Includes

  • If Hepatitis B Surface Antigen is positive, then confirmatory testing based on the manufacturer's FDA approved recommendations will be performed at an additional charge (CPT code(s): 87341).

Methodology

Immunoassay (IA)

Reference Range(s)

Non-Reactive

Alternative Name(s)

Australian Antigen,Hep B,HBsAg

LOINC® Codes, Performing Laboratory

Service Area must be determined
If Hepatitis B Surface Antigen is positive, then confirmatory testing based on the manufacturer's FDA approved recommendations will be performed at an additional charge (CPT code(s): 87341).

Methodology

Immunoassay (IA)

Reference Range(s)

Non-Reactive

Alternative Name(s)

Australian Antigen,Hep B,HBsAg
Service Area must be determined

Preferred Specimen(s)

2 mL serum

Alternative Specimen(s)

Plasma collected in: EDTA (lavender-top) tube

Minimum Volume

1 mL

Collection Instructions

Dietary supplements containing biotin may interfere in assays and may skew analyte results to be either falsely high or falsely low. For patients receiving the recommended daily doses of biotin, draw samples at least 8 hours following the last biotin supplementation. For patients on mega-doses of biotin supplements, draw samples at least 72 hours following the last biotin supplementation.

Note: When only a single test, Hepatitis B Surface Antigen, is ordered to diagnose Hepatitis B in a pregnant woman, additional tests such as liver enzymes should be ordered to confirm the diagnosis.

Transport Container

Serum separator tube (SST)

Transport Temperature

Room temperature

Specimen Stability

  • Room temperature: 7 days

  • Refrigerated: 14 days
  • Frozen: 30 days

Reject Criteria

Gross hemolysis • Grossly lipemic

Setup Schedule

Service Area must be determined
2 mL serum
Plasma collected in: EDTA (lavender-top) tube
1 mL

Dietary supplements containing biotin may interfere in assays and may skew analyte results to be either falsely high or falsely low. For patients receiving the recommended daily doses of biotin, draw samples at least 8 hours following the last biotin supplementation. For patients on mega-doses of biotin supplements, draw samples at least 72 hours following the last biotin supplementation.

Note: When only a single test, Hepatitis B Surface Antigen, is ordered to diagnose Hepatitis B in a pregnant woman, additional tests such as liver enzymes should be ordered to confirm the diagnosis.

Serum separator tube (SST)
Room temperature

Room temperature: 7 days
Refrigerated: 14 days
Frozen: 30 days

Gross hemolysis • Grossly lipemic
Service Area must be determined
In-home collection may be available in your area for purchase through Quest Mobile.
Test Details

Clinical Significance

Test Resources

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

The CPT codes provided are based on AMA guidance and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

This material contains content from LOINC® (http://loinc.org). The LOINC Table, LOINC Table Core are copyright © 1995-2019, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license.

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