Desipramine
Test Code
412
80335 (HCPCS: G0480)
Clinical Significance
Desipramine - Desipramine is a tricyclic antidepressant. Therapeutic drug levels are monitored to assist the physician assessing therapeutic response and to avoid toxicity.
Test Resources
Test Details
Collect at steady-state trough concentration. Specimen should be collected >12 hours after dose.
Methodology
Chromatography/Mass Spectrometry
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Reference Range(s)
50-300 mcg/L
Alternative Name(s)
Pertofran, Norpramin®
Preferred Specimen(s)
3 mL serum collected in a red-top tube (no gel)
Alternative Specimen(s)
Plasma collected in: EDTA (lavender-top) tube, sodium heparin (green-top) tube, or lithium heparin (green-top) tube
Minimum Volume
1.5 mL
Transport Container
Transport tube
Transport Temperature
Room temperature
Specimen Stability
- Room temperature: 5 days
- Refrigerated: 5 days
- Frozen: 30 days
Reject Criteria
Gross hemolysis • Gel barrier/Serum separator tube (SST)
Setup Schedule
3 mL serum collected in a red-top tube (no gel)
Plasma collected in: EDTA (lavender-top) tube, sodium heparin (green-top) tube, or lithium heparin (green-top) tube
1.5 mL
Transport tube
Room temperature
Room temperature: 5 days
Refrigerated: 5 days
Frozen: 30 days
Refrigerated: 5 days
Frozen: 30 days
Gross hemolysis • Gel barrier/Serum separator tube (SST)