Plasma Creatine Guanidinoacetate

Plasma Creatine Guanidinoacetate

Test Code

40070
82540, 82542
40070
82540, 82542
This test is not available in all locations. Please provide SERVICE AREA INFORMATION to confirm Test Code for the lab that services your account or to find available tests you can order.
In-home collection is not available in your area through Quest Mobile.

Clinical Significance

Plasma Creatine Guanidinoacetate - This test is designed to assess abnormalities in the synthesis of creatine. Three disorders in the synthesis and transport of creatine have been recognized recently. Guanidinoacetate methyltransferase (GAMT) deficiency was the first inborn error of creatine biosynthesis in man. More recently, arginine: Glycine amidinotransferase (AGAT) and creatine transporter deficiencies have been reported. GAMT deficiency results in creatine and creatine phosphate deficiency and leads to an elevation of guanidinoacetate in physiological fluids. The other disorders may also lead to alterations in the levels of ...

Test Resources

None found for this test
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Test Details

Includes

  • Creatine, Guanidinoacetate, Interpretation

Methodology

Tandem Mass Spectroscopy

Reference Range(s)

See Laboratory Report

LOINC® Codes, Performing Laboratory

Service Area must be determined
Creatine, Guanidinoacetate, Interpretation

Methodology

Tandem Mass Spectroscopy

Reference Range(s)

See Laboratory Report
Service Area must be determined

Preferred Specimen(s)

1 mL plasma collected in a sodium heparin (green-top) tube

Collection Instructions

Draw blood in sodium Heparin (green-top) tube(s) and separate as soon as possible. Send 1-2 cc of plasma. Store the specimen frozen at -20° C. Specimen may be stored frozen for up to 7 days.

Transport Container

Transport tube

Transport Temperature

Frozen

Specimen Stability

  • Room temperature: Not acceptable
  • Refrigerated: Not acceptable

Reject Criteria

Received room temperature • Received refrigerated

Setup Schedule

Service Area must be determined
1 mL plasma collected in a sodium heparin (green-top) tube
Draw blood in sodium Heparin (green-top) tube(s) and separate as soon as possible. Send 1-2 cc of plasma. Store the specimen frozen at -20° C. Specimen may be stored frozen for up to 7 days.
Transport tube
Frozen
Room temperature: Not acceptable
Refrigerated: Not acceptable
Received room temperature • Received refrigerated
Service Area must be determined
This test is not available in all locations. Please provide ACCOUNT INFORMATION NEEDED to confirm Test Code for the lab that services your account or to find available tests you can order.
In-home collection is not available in your area through Quest Mobile.
Test Details

Clinical Significance

Test Resources

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

The CPT codes provided are based on AMA guidance and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

This material contains content from LOINC® (http://loinc.org). The LOINC Table, LOINC Table Core are copyright © 1995-2019, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license.

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