N-Methylhistamine, Random, Urine
Test Code
Clinical Significance
N-Methylhistamine, Random, Urine - Screening for and monitoring of mastocytosis and disorders of systemic mast-cell activation, such as anaphylaxis and other forms of severe systemic allergic reactions using random urine specimens.
Monitoring therapeutic progress in conditions that are associated with secondary, localized, low-grade persistent, mast-cell proliferation and activation such as interstitial cystitis.
Test Resources
Please visit our Clinical Education Center to stay informed on any future publications, webinars, or other education opportunities.
Test Details
Methodology
Reference Range(s)
| 0-5 years | 120-510 mcg/g Cr |
| 6-16 years | 70-330 mcg/g Cr |
| >16 years | 30-200 mcg/g Cr |
| Creatinine, Random, Urine | See Laboratory Report |
Preferred Specimen(s)
5 mL urine collected in a sterile, screw-cap container with no preservative
Minimum Volume
3 mL
Collection Instructions
1. Collect a random urine specimen within a few hours of symptom onset.
2. No preservative
Advisory Information: Patients with chronic mast cell activation often have chronically elevated N-methylhistamine (NMH) levels and will sometimes have intermittent NMH elevations. In these cases, a 24-hour urine collection is preferred. See 39559-N-Methylhistamine, 24 Hour, Urine.
Transport Container
Plastic urine container
Transport Temperature
Frozen
Specimen Stability
- Room temperature: 14 days
- Refrigerated: 28 days
- Frozen: 28 days
Setup Schedule
2. No preservative
Advisory Information: Patients with chronic mast cell activation often have chronically elevated N-methylhistamine (NMH) levels and will sometimes have intermittent NMH elevations. In these cases, a 24-hour urine collection is preferred. See 39559-N-Methylhistamine, 24 Hour, Urine.
Refrigerated: 28 days
Frozen: 28 days