HBV Triple Screen Panel with Reflexes

HBV Triple Screen Panel with Reflexes

Test Code

39170
87340, 86704, 86317
CPT Code is subject to a Medicare Limited Coverage Policy and may require a signed ABN when ordering.
39170
87340, 86704, 86317
CPT Code is subject to a Medicare Limited Coverage Policy and may require a signed ABN when ordering.
In-home collection may be available in your area for purchase through Quest Mobile.

Clinical Significance

HBV Triple Screen Panel with Reflexes - This panel consists of the three tests recommended by the Centers for Disease Control and Prevention for screening for hepatitis B infection: 1) hepatitis B surface antigen (HBsAg); 2) antibody to hepatitis B surface antigen (anti-HBs); 3) total antibody to hepatitis B core antigen (anti-HBc). Low positive HBsAg samples will be confirmed by a HBsAg neutralization test. Reactive total anti-HBc samples will reflex to an anti-HBc IgM test.

This panel can be ordered for universal HBV screening in all adults, including pregnant persons and patients who are at increased risk of acquiring HBV. ...

Test Details

Includes

  • Interpretation
  • Hepatitis B Surface Antigen with Reflex Confirmation
  • Hepatitis B Core Antibody, Total, with Reflex to IgM
  • Hepatitis B Surface Antibody, Quantitative
  •  
  • Positive Hepatitis B Surface Antigen samples will be confirmed based on the manufacturer's FDA approved recommendations at an additional charge (CPT code(s): 87341).
  • If Hepatitis B Core Antibody Total is reactive, then Hepatitis B Core IgM Antibody will be performed at an additional charge (CPT code(s): 86705).

Methodology

Immunoassay (IA)

Reference Range(s)

InterpretationSee Laboratory Report
Hepatitis B Surface AntigenNon-Reactive
Hepatitis B Core Antibody, TotalNon-Reactive
Hepatitis B Surface Ab, Quant≥10 mIU/mL

Alternative Name(s)

HBV Staging Serology Screening, Hepatitis B Acute/Chronic Screening, HBV Serological Assessment, Hep B screening, Hep B panel, Hep B serology

LOINC® Codes, Performing Laboratory

Interpretation
Hepatitis B Surface Antigen with Reflex Confirmation
Hepatitis B Core Antibody, Total, with Reflex to IgM
Hepatitis B Surface Antibody, Quantitative

Positive Hepatitis B Surface Antigen samples will be confirmed based on the manufacturer's FDA approved recommendations at an additional charge (CPT code(s): 87341).
If Hepatitis B Core Antibody Total is reactive, then Hepatitis B Core IgM Antibody will be performed at an additional charge (CPT code(s): 86705).

Methodology

Immunoassay (IA)

Reference Range(s)

InterpretationSee Laboratory Report
Hepatitis B Surface AntigenNon-Reactive
Hepatitis B Core Antibody, TotalNon-Reactive
Hepatitis B Surface Ab, Quant≥10 mIU/mL

Alternative Name(s)

HBV Staging Serology Screening, Hepatitis B Acute/Chronic Screening, HBV Serological Assessment, Hep B screening, Hep B panel, Hep B serology

Preferred Specimen(s)

4 mL serum

Alternative Specimen(s)

Plasma collected in: EDTA (lavender-top) tube

Minimum Volume

3 mL

Collection Instructions

Dietary supplements containing biotin may interfere in assays and may skew analyte results to be either falsely high or falsely low. For patients receiving the recommended daily doses of biotin, draw samples at least 8 hours following the last biotin supplementation. For patients on mega-doses of biotin supplements, draw samples at least 72 hours following the last biotin supplementation.

Transport Container

Serum separator tube (SST)

Transport Temperature

Room temperature

Specimen Stability

  • Room temperature: 5 days
  • Refrigerated: 14 days
  • Frozen: 21 days

Reject Criteria

Gross hemolysis • Grossly lipemic

Setup Schedule

4 mL serum
Plasma collected in: EDTA (lavender-top) tube
3 mL
Dietary supplements containing biotin may interfere in assays and may skew analyte results to be either falsely high or falsely low. For patients receiving the recommended daily doses of biotin, draw samples at least 8 hours following the last biotin supplementation. For patients on mega-doses of biotin supplements, draw samples at least 72 hours following the last biotin supplementation.
Serum separator tube (SST)
Room temperature
Room temperature: 5 days
Refrigerated: 14 days
Frozen: 21 days
Gross hemolysis • Grossly lipemic
In-home collection may be available in your area for purchase through Quest Mobile.
Test Details

Clinical Significance

Test Resources

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

The CPT codes provided are based on AMA guidance and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

This material contains content from LOINC® (http://loinc.org). The LOINC Table, LOINC Table Core are copyright © 1995-2019, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license.

The tests listed by specialty and category are a select group of tests offered. For a complete list of Quest Diagnostics tests, please adjust the filter options chosen, or refer to our Directory of Services.