HBV Triple Screen Panel with Reflexes
Test Code
Clinical Significance
HBV Triple Screen Panel with Reflexes - This panel consists of the three tests recommended by the Centers for Disease Control and Prevention for screening for hepatitis B infection: 1) hepatitis B surface antigen (HBsAg); 2) antibody to hepatitis B surface antigen (anti-HBs); 3) total antibody to hepatitis B core antigen (anti-HBc). Low positive HBsAg samples will be confirmed by a HBsAg neutralization test. Reactive total anti-HBc samples will reflex to an anti-HBc IgM test.
This panel can be ordered for universal HBV screening in all adults, including pregnant persons and patients who are at increased risk of acquiring HBV. ...
Test Resources
Test FAQ
HBV Screen Panel with ReflexesTest Summary
HBV Triple Screen Panel With ReflexesTest Details
Hepatitis B Surface Antigen with Reflex Confirmation
Hepatitis B Core Antibody, Total, with Reflex to IgM
Hepatitis B Surface Antibody, Quantitative
Positive Hepatitis B Surface Antigen samples will be confirmed based on the manufacturer's FDA approved recommendations at an additional charge (CPT code(s): 87341).
If Hepatitis B Core Antibody Total is reactive, then Hepatitis B Core IgM Antibody will be performed at an additional charge (CPT code(s): 86705).
Methodology
Reference Range(s)
| Interpretation | See Laboratory Report |
| Hepatitis B Surface Antigen | Non-Reactive |
| Hepatitis B Core Antibody, Total | Non-Reactive |
| Hepatitis B Surface Ab, Quant | ≥10 mIU/mL |
Alternative Name(s)
Preferred Specimen(s)
4 mL serum
Alternative Specimen(s)
Plasma collected in: EDTA (lavender-top) tube
Minimum Volume
3 mL
Collection Instructions
Dietary supplements containing biotin may interfere in assays and may skew analyte results to be either falsely high or falsely low. For patients receiving the recommended daily doses of biotin, draw samples at least 8 hours following the last biotin supplementation. For patients on mega-doses of biotin supplements, draw samples at least 72 hours following the last biotin supplementation.
Transport Container
Serum separator tube (SST)
Transport Temperature
Room temperature
Specimen Stability
- Room temperature: 5 days
- Refrigerated: 14 days
- Frozen: 21 days
Reject Criteria
Gross hemolysis • Grossly lipemic
Setup Schedule
Refrigerated: 14 days
Frozen: 21 days