Biotin (Vitamin B7)

Test code

391

CPT code(s)*

84591

In-home collection is not available in your area through Quest Mobile.

Clinical significance

Biotin (Vitamin B7) - Biotin, vitamin B7, or vitamin H, is a water soluble vitamin. The vitamin plays a role in the transferring of carbon dioxide in the metabolism of fat, carbohydrate and protein by functioning as an enzyme cofactor. It is involved in multiple biochemical reactions including niacin metabolism, amino acid degradation, and the formation of purine, which is an integral part of nucleic acids. It interacts with histone by the action of biotinyl-transferase. Sometimes the vitamin is used in weight reduction programs. It may be prescribed as a supplement for diabetic patients due to its role in carbohydrate metabolism. Biotin is commonly found in vitamin B complex and…

Test resources

None found for this test
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Details

Test details

Methodology

Bioassay (BA)

Assay category

The performance characteristics of the listed assay was validated by BioAgilytix Diagnostics. The US FDA has not approved or cleared this test. The results of this assay can be used for clinical diagnosis without FDA approval. BioAgilytix Diagnostics is a CLIA certified, CAP accredited laboratory for performing high complexity assays such as this one.

Specimen requirements
Patient preparation	None Specified
Preferred specimen(s)	2 mL frozen serum - protect from light
Minimum volume	1 mL
Collection instructions	Allow sample to clot for 30 minutes, spin at 3000 rpm for 10 minutes and transfer serum to a plastic amber vial. If amber vial is not available, wrap tube in aluminum foil to protect from light. Freeze within 30 minutes and send frozen.
Transport container	Transport tube
Transport temperature	Frozen
Specimen stability	Room temperature: Unacceptable Refrigerated: 7 days Frozen: 14 days
Reject criteria	Gross hemolysis • Lipemia • Received room temperature • Not protected from light • Samples other than serum

Reference range(s)

Reference Range(s)

<12 years	100.0-2460.2 pg/mL
≥12 years	221.0-3004.0 pg/mL

LOINC® codes

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NOTE: The codes listed in the table are not orderable Test Codes

Result code	Result name	LOINC code	Component name
86002010	BIOTIN (VITAMIN B7)	1980-2	Biotin

Performing lab & setup schedule

Performing laboratory

Cambridge Biomedical Research Group

1320 Soldiers Field Road

Boston, MA 02135-1020

Setup schedule

Set up: Varies; Report available: 10 days

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

*The CPT codes provided are based on AMA guidance and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

This material contains content from LOINC® (http://loinc.org). The LOINC Table, LOINC Table Core are copyright © 1995-2019, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license.

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