Biotin (Vitamin B7)

Biotin (Vitamin B7)

Test Code

391
84591
CPT Code is subject to a Medicare Limited Coverage Policy and may require a signed ABN when ordering.
391
84591
CPT Code is subject to a Medicare Limited Coverage Policy and may require a signed ABN when ordering.
Not offered in Quest Diagnostics Nichols Institute (IFD) – San Juan Capistrano. Please provide SERVICE AREA INFORMATION to find available tests you can order.
In-home collection is not available in your area through Quest Mobile.

Clinical Significance

Biotin (Vitamin B7) - Biotin, vitamin B7, or vitamin H, is a water soluble vitamin. The vitamin plays a role in the transferring of carbon dioxide in the metabolism of fat, carbohydrate and protein by functioning as an enzyme cofactor. It is involved in multiple biochemical reactions including niacin metabolism, amino acid degradation, and the formation of purine, which is an integral part of nucleic acids. It interacts with histone by the action of biotinyl-transferase. Sometimes the vitamin is used in weight reduction programs. It may be prescribed as a supplement for diabetic patients due to its role in carbohydrate ...

Test Resources

None found for this test
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Test Details

Methodology

Bioassay (BA)

Assay Category

The performance characteristics of the listed assay was validated by BioAgilytix Diagnostics. The US FDA has not approved or cleared this test. The results of this assay can be used for clinical diagnosis without FDA approval. BioAgilytix Diagnostics is a CLIA certified, CAP accredited laboratory for performing high complexity assays such as this one.

Reference Range(s)

<12 years 100.0-2460.2 pg/mL
≥12 years 221.0-3004.0 pg/mL

LOINC® Codes, Performing Laboratory

Service Area must be determined

Methodology

Bioassay (BA)
The performance characteristics of the listed assay was validated by BioAgilytix Diagnostics. The US FDA has not approved or cleared this test. The results of this assay can be used for clinical diagnosis without FDA approval. BioAgilytix Diagnostics is a CLIA certified, CAP accredited laboratory for performing high complexity assays such as this one.

Reference Range(s)

<12 years 100.0-2460.2 pg/mL
≥12 years 221.0-3004.0 pg/mL
Service Area must be determined

Preferred Specimen(s)

2 mL frozen serum - protect from light

Minimum Volume

1 mL

Collection Instructions

Allow sample to clot for 30 minutes, spin at 3000 rpm for 10 minutes and transfer serum to a plastic amber vial. If amber vial is not available, wrap tube in aluminum foil to protect from light. Freeze within 30 minutes and send frozen.

Transport Container

Transport tube

Transport Temperature

Frozen

Specimen Stability

  • Room temperature: Unacceptable
  • Refrigerated: 7 days
  • Frozen: 14 days

Reject Criteria

Gross hemolysis • Lipemia • Received room temperature • Not protected from light • Samples other than serum

Setup Schedule

Service Area must be determined
2 mL frozen serum - protect from light
1 mL
Allow sample to clot for 30 minutes, spin at 3000 rpm for 10 minutes and transfer serum to a plastic amber vial. If amber vial is not available, wrap tube in aluminum foil to protect from light. Freeze within 30 minutes and send frozen.
Transport tube
Frozen
Room temperature: Unacceptable
Refrigerated: 7 days
Frozen: 14 days
Gross hemolysis • Lipemia • Received room temperature • Not protected from light • Samples other than serum
Service Area must be determined
Not offered in Quest Diagnostics Nichols Institute (IFD) – San Juan Capistrano. Please provide SERVICE AREA INFORMATION to find available tests you can order.
In-home collection is not available in your area through Quest Mobile.
Test Details

Clinical Significance

Test Resources

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

The CPT codes provided are based on AMA guidance and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

This material contains content from LOINC® (http://loinc.org). The LOINC Table, LOINC Table Core are copyright © 1995-2019, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license.

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