Soluble Liver Antigen (SLA) Autoantibody

Test code

38928

CPT code(s)*

83520

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Clinical significance

Soluble Liver Antigen (SLA) Autoantibody - Anti-soluble liver antigen antibodies are detected in 10-30% of patients with type 1 autoimmune hepatitis (AIH), but not in patients with type 2 AIH, primary sclerosing cholangitis or primary biliary cirrhosis. The antibody is directed against a UGA suppressor tRNA-associated protein. In some patients with AIH, this antibody may be the only autoantibody detected by current assays.

Test resources

None found for this test
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Details

Test details

Methodology

Immunoassay (IA)

Specimen requirements
Patient preparation	None Specified
Preferred specimen(s)	1 mL serum
Minimum volume	0.3 mL
Transport container	Transport tube
Transport temperature	Refrigerated (cold packs)
Specimen stability	Room temperature: 48 hours Refrigerated: 8 days Frozen: 28 days
Reject criteria	Gross hemolysis • Lipemia

Reference range(s)

Reference Range(s)

<20.1 U	Negative
20.1-24.9 U	Equivocal
≥25.0 U	Positive

LOINC® codes

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NOTE: The codes listed in the table are not orderable Test Codes

Result code	Result name	LOINC code	Component name
85997531	SOLUBLE LIVER ANTIGEN (SLA) AUTOANTIBODY	32219-8	Soluble liver Ab

Performing lab & setup schedule

Performing laboratory

Quest Diagnostics Nichols Institute-Chantilly VA

14225 Newbrook Drive

Chantilly, VA 20151-2228

Setup schedule

Set up: Tues, Thurs

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

*The CPT codes provided are based on AMA guidance and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

This material contains content from LOINC® (http://loinc.org). The LOINC Table, LOINC Table Core are copyright © 1995-2019, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license.

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