Soluble Liver Antigen (SLA) Autoantibody
Test Code
38928
83520
Clinical Significance
Soluble Liver Antigen (SLA) Autoantibody - Anti-soluble liver antigen antibodies are detected in 10-30% of patients with type 1 autoimmune hepatitis (AIH), but not in patients with type 2 AIH, primary sclerosing cholangitis or primary biliary cirrhosis. The antibody is directed against a UGA suppressor tRNA-associated protein. In some patients with AIH, this antibody may be the only autoantibody detected by current assays.
Test Resources
None found for this test
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Test Details
Methodology
Immunoassay (IA)
Reference Range(s)
| <20.1 U | Negative |
| 20.1-24.9 U | Equivocal |
| ≥25.0 U | Positive |
Preferred Specimen(s)
1 mL serum
Minimum Volume
0.3 mL
Transport Container
Transport tube
Transport Temperature
Refrigerated (cold packs)
Specimen Stability
- Room temperature: 48 hours
- Refrigerated: 8 days
- Frozen: 28 days
Reject Criteria
Gross hemolysis • Lipemia
Setup Schedule
1 mL serum
0.3 mL
Transport tube
Refrigerated (cold packs)
Room temperature: 48 hours
Refrigerated: 8 days
Frozen: 28 days
Refrigerated: 8 days
Frozen: 28 days
Gross hemolysis • Lipemia