Soluble Liver Antigen (SLA) Autoantibody

Soluble Liver Antigen (SLA) Autoantibody

Test Code

38928
83520
38928
83520
In-home collection may be available in your area for purchase through Quest Mobile.

Clinical Significance

Soluble Liver Antigen (SLA) Autoantibody - Anti-soluble liver antigen antibodies are detected in 10-30% of patients with type 1 autoimmune hepatitis (AIH), but not in patients with type 2 AIH, primary sclerosing cholangitis or primary biliary cirrhosis. The antibody is directed against a UGA suppressor tRNA-associated protein. In some patients with AIH, this antibody may be the only autoantibody detected by current assays.

Test Resources

None found for this test
Please visit our Clinical Education Center to stay informed on any future publications, webinars, or other education opportunities.

Test Details

Methodology

Immunoassay (IA)

Reference Range(s)

<20.1 U Negative
20.1-24.9 U Equivocal
≥25.0 U Positive

LOINC® Codes, Performing Laboratory

Methodology

Immunoassay (IA)

Reference Range(s)

<20.1 U Negative
20.1-24.9 U Equivocal
≥25.0 U Positive

Preferred Specimen(s)

1 mL serum

Minimum Volume

0.3 mL

Transport Container

Transport tube

Transport Temperature

Refrigerated (cold packs)

Specimen Stability

  • Room temperature: 48 hours
  • Refrigerated: 8 days
  • Frozen: 28 days

Reject Criteria

Gross hemolysis • Lipemia

Setup Schedule

1 mL serum
0.3 mL
Transport tube

Refrigerated (cold packs)

Room temperature: 48 hours
Refrigerated: 8 days
Frozen: 28 days
Gross hemolysis • Lipemia
In-home collection may be available in your area for purchase through Quest Mobile.
Test Details

Clinical Significance

Test Resources

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

The CPT codes provided are based on AMA guidance and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

This material contains content from LOINC® (http://loinc.org). The LOINC Table, LOINC Table Core are copyright © 1995-2019, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license.

The tests listed by specialty and category are a select group of tests offered. For a complete list of Quest Diagnostics tests, please adjust the filter options chosen, or refer to our Directory of Services.