Total Glutathione in Whole Blood

Test code

38813

CPT code(s)*

82978

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Clinical significance

Total Glutathione in Whole Blood - Glutathione is a tripeptide formed by a peptide linkage between the amine group of cysteine linked to glycine and the carboxyl group of the glutamate side-chain. It is an abundant cellular reducing agent, whose major biological function is mitigating oxidative damage to biological macromolecules. Glutathione is also important in the metabolism and excretion of xenobiotic compounds. Glutathione is consumed to maintain cells in a reduced condition. Consequently, glutathione levels in patient samples are expected to be diminished in disease states where oxygen reactive species are involved, such as rheumatoid arthritis and atherosclerosis. Low…

Test resources

None found for this test
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Details

Test details

Methodology

Kinetic

Assay category

The performance characteristics of the listed assay was validated by BioAgilytix Diagnostics. The US FDA has not approved or cleared this test. The results of this assay can be used for clinical diagnosis without FDA approval. BioAgilytix Diagnostics is a CLIA certified, CAP accredited laboratory for performing high complexity assays such as this one.

Specimen requirements
Patient preparation	None Specified
Preferred specimen(s)	1 full tube of whole blood collected in an ACD solution B (yellow-top) tube
Minimum volume	1 full tube
Collection instructions	Do not centrifuge. Send whole tube. Solution B specimen volume is 6 mL. ACD collection tubes must be >50% filled in order to ensure proper mixture of ACD solution.
Transport container	ACD solution B (yellow-top) tube
Transport temperature	Refrigerated (cold packs)
Specimen stability	Room temperature: Unacceptable Refrigerated: 21 days Frozen: Unacceptable
Reject criteria	Hemolysis • Samples oversaturated with ACD solution

Reference range(s)

373-838 uM

LOINC® codes

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Service Area Information

Performing lab & setup schedule

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Service Area Information

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

*The CPT codes provided are based on AMA guidance and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

This material contains content from LOINC® (http://loinc.org). The LOINC Table, LOINC Table Core are copyright © 1995-2019, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license.

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