TRAb (TSH Receptor Binding Antibody)
Test Code
38683
83520
In-home collection is not available in your area through Quest Mobile.
Clinical Significance
TRAb (TSH Receptor Binding Antibody) - Measurement of TRAb is used to diagnose and manage Graves' disease, neonatal hypothyroidism, and postpartum thyroid dysfunction. TRAb, which measures the ability of antibodies to inhibit TSH binding to its receptor, reflects the presence of either or both the stimulatory and inhibitory immunoglobulin classes.
Test Resources
Clinical Focus
Thyroid Dysfunction in Nonpregnant AdultsTest Details
Methodology
Enzyme Linked Immunosorbent Assay (ELISA)
Reference Range(s)
≤2.00 IU/L
Alternative Name(s)
Thyrotropin Receptor Antibody,TSH Receptor Binding Antibody,Thyrotropin Binding (TBII),TBII
Preferred Specimen(s)
1 mL serum
Minimum Volume
0.5 mL
Collection Instructions
Allow serum to clot at room temperature. Serum must be separated from the cells or gel barrier within 1 hour of collection and poured into a transport vial.
Transport Container
Transport tube
Transport Temperature
Room temperature
Specimen Stability
- Room temperature: 7 days
- Refrigerated: 14 days
- Frozen: 21 days
Reject Criteria
Gross hemolysis • Serum received in a gel barrier tube or on the cells
Setup Schedule
1 mL serum
0.5 mL
Allow serum to clot at room temperature. Serum must be separated from the cells or gel barrier within 1 hour of collection and poured into a transport vial.
Transport tube
Room temperature
Room temperature: 7 days
Refrigerated: 14 days
Frozen: 21 days
Refrigerated: 14 days
Frozen: 21 days
Gross hemolysis • Serum received in a gel barrier tube or on the cells