Lipoprotein Fractionation, NMR

Lipoprotein Fractionation, NMR

Test Code

37847
83704
CPT Code is subject to a Medicare Limited Coverage Policy and may require a signed ABN when ordering.
37847
83704
CPT Code is subject to a Medicare Limited Coverage Policy and may require a signed ABN when ordering.
Not offered in Quest Diagnostics Nichols Institute (IFD) – San Juan Capistrano. Please provide SERVICE AREA INFORMATION to find available tests you can order.
In-home collection may be available in your area for purchase through Quest Mobile.

Clinical Significance

Lipoprotein Fractionation, NMR - The Lipoprotein Fractionation, NMR test is used to help assess the risk for cardiovascular disease (CVD) in patients with intermediate or high risk based on traditional or emerging risk factors, and to assess therapeutic response in patients undergoing lipid-lowering therapy.

Test Resources

None found for this test
Please visit our Clinical Education Center to stay informed on any future publications, webinars, or other education opportunities.

Test Details

Includes

  • LDL P, Small LDL P, LDL Size
  • HDL P, Large HDL P, HDL Size
  • Large VLDL P, VLDL Size

Patient Preparation

Patient should be fasting 12 hours

Methodology

Nuclear Magnetic Resonance

Assay Category

This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics Cardiometabolic Center of Excellence at Cleveland HeartLab. It has not been cleared or approved by the U.S. Food and Drug Administration. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Reference Range(s)

See Laboratory Report

LOINC® Codes, Performing Laboratory

Service Area must be determined
LDL P, Small LDL P, LDL Size
HDL P, Large HDL P, HDL Size
Large VLDL P, VLDL Size
Patient should be fasting 12 hours

Methodology

Nuclear Magnetic Resonance
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics Cardiometabolic Center of Excellence at Cleveland HeartLab. It has not been cleared or approved by the U.S. Food and Drug Administration. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Reference Range(s)

See Laboratory Report
Service Area must be determined

Preferred Specimen(s)

2 mL serum collected in a red-top tube (no gel)

Minimum Volume

1 mL

Collection Instructions

1. Gently invert draw tube 5X (DO NOT SHAKE).
2. Let blood clot for 30-60 minutes at room temperature.
3. Centrifuge for 10 minutes.
4. Aliquot top layer from red-top draw tube and place SERUM in transport tube and dispose of draw tube. Label the transport tube as "No Additive Serum Red". ONLY ship No Additive Serum in transport tube.
5. Store and transport refrigerated. Specimen is stable at -20° for 10 days and -70° for 28 days but CANNOT BE SHIPPED ON DRY ICE.

Note: Adults without other risk factors for heart disease should receive a lipid panel once every five years. Individuals who have had an abnormal lipid panel, or those who have other cardiovascular risk factors, may be tested more frequently.

Transport Container

Transport tube

Transport Temperature

Refrigerated (cold packs)

Specimen Stability

  • Room temperature: Unacceptable
    Refrigerated: 7 days
    Frozen -20° C: Unacceptable
    Frozen -70° C: Unacceptable

Reject Criteria

Gross hemolysis • Grossly lipemic • Serum separator tube (SST) • Sample received on dry ice

Setup Schedule

Service Area must be determined
2 mL serum collected in a red-top tube (no gel)
1 mL
1. Gently invert draw tube 5X (DO NOT SHAKE).
2. Let blood clot for 30-60 minutes at room temperature.
3. Centrifuge for 10 minutes.
4. Aliquot top layer from red-top draw tube and place SERUM in transport tube and dispose of draw tube. Label the transport tube as "No Additive Serum Red". ONLY ship No Additive Serum in transport tube.
5. Store and transport refrigerated. Specimen is stable at -20° for 10 days and -70° for 28 days but CANNOT BE SHIPPED ON DRY ICE.

Note: Adults without other risk factors for heart disease should receive a lipid panel once every five years. Individuals who have had an abnormal lipid panel, or those who have other cardiovascular risk factors, may be tested more frequently.
Transport tube
Refrigerated (cold packs)
Room temperature: Unacceptable
Refrigerated: 7 days
Frozen -20° C: Unacceptable
Frozen -70° C: Unacceptable
Gross hemolysis • Grossly lipemic • Serum separator tube (SST) • Sample received on dry ice
Service Area must be determined
Not offered in Quest Diagnostics Nichols Institute (IFD) – San Juan Capistrano. Please provide SERVICE AREA INFORMATION to find available tests you can order.
In-home collection may be available in your area for purchase through Quest Mobile.
Test Details

Clinical Significance

Test Resources

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

The CPT codes provided are based on AMA guidance and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

This material contains content from LOINC® (http://loinc.org). The LOINC Table, LOINC Table Core are copyright © 1995-2019, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license.

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