Sickle Cell Screen with Reflex to Hemoglobinopathy Evaluation

Sickle Cell Screen with Reflex to Hemoglobinopathy Evaluation

Test Code

37679
85660
37679
85660
Not offered in Quest Diagnostics Nichols Institute (IFD) – San Juan Capistrano. Please provide SERVICE AREA INFORMATION to confirm Test Code for the lab that services your account or to find available tests you can order.
In-home collection may be available in your area for purchase through Quest Mobile.

Clinical Significance

Sickle Cell Screen with Reflex to Hemoglobinopathy Evaluation - Screening test to determine presence of sickling hemoglobins (e.g. hemoglobin-S Hemoglobin C-Harlem).

Test Resources

None found for this test
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Test Details

Includes

  • If Sickle Cell Screen is Positive, then Hemoglobinopathy Evaluation will be performed at an additional charge (CPT code(s): 83020, 85014, 85018, 85041).

    Hemoglobinopathy Evaluation includes: Hemoglobin A, Hemoglobin F, Hemoglobin A2 (Quant), Hemoglobin S, Hemoglobin C, Hemoglobin E, and any hemoglobin variants
    Red Blood Cell Count, Hemoglobin, Hematocrit, MCV, MCH, RDW

Methodology

Solubility

Reference Range(s)

Sickle Cell ScreenNegative

LOINC® Codes, Performing Laboratory

Service Area must be determined
If Sickle Cell Screen is Positive, then Hemoglobinopathy Evaluation will be performed at an additional charge (CPT code(s): 83020, 85014, 85018, 85041).

Hemoglobinopathy Evaluation includes: Hemoglobin A, Hemoglobin F, Hemoglobin A2 (Quant), Hemoglobin S, Hemoglobin C, Hemoglobin E, and any hemoglobin variants
Red Blood Cell Count, Hemoglobin, Hematocrit, MCV, MCH, RDW

Methodology

Solubility

Reference Range(s)

Sickle Cell ScreenNegative
Service Area must be determined

Preferred Specimen(s)

4 mL whole blood collected in an EDTA (lavender-top) tube

Alternative Specimen(s)

Whole blood collected in: EDTA (tan-top), (pink-top) or (royal blue-top) tube

Minimum Volume

1 mL

Collection Instructions

Maintain specimen at room temperature. Do not centrifuge. Patient age and ethnicity are necessary for proper interpretation. Blood transfusions within the last 4 months may affect results.

Note: This test is not appropriate for patients less than 6 months old due to interference by Hemoglobin F. In these cases it is suggested that test code 35489 (Hemoglobinopathy Evaluation) be ordered. If tube drawn is shared with lead testing, trace metal-free EDTA (i.e. royal blue-top or tan-top) tube is required.

Transport Container

EDTA (lavender-top) tube

Transport Temperature

Room temperature

Specimen Stability

  • Room temperature: 72 hours
    Refrigerated: 7 days
    Frozen: Unacceptable

Reject Criteria

Gross hemolysis • Grossly lipemic • Clotted

Setup Schedule

Service Area must be determined
4 mL whole blood collected in an EDTA (lavender-top) tube
Whole blood collected in: EDTA (tan-top), (pink-top) or (royal blue-top) tube
1 mL
Maintain specimen at room temperature. Do not centrifuge. Patient age and ethnicity are necessary for proper interpretation. Blood transfusions within the last 4 months may affect results.

Note: This test is not appropriate for patients less than 6 months old due to interference by Hemoglobin F. In these cases it is suggested that test code 35489 (Hemoglobinopathy Evaluation) be ordered. If tube drawn is shared with lead testing, trace metal-free EDTA (i.e. royal blue-top or tan-top) tube is required.
EDTA (lavender-top) tube
Room temperature
Room temperature: 72 hours
Refrigerated: 7 days
Frozen: Unacceptable
Gross hemolysis • Grossly lipemic • Clotted
Service Area must be determined
Not offered in Quest Diagnostics Nichols Institute (IFD) – San Juan Capistrano. Please provide SERVICE AREA INFORMATION to confirm Test Code for the lab that services your account or to find available tests you can order.
In-home collection may be available in your area for purchase through Quest Mobile.
Test Details

Clinical Significance

Test Resources

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

The CPT codes provided are based on AMA guidance and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

This material contains content from LOINC® (http://loinc.org). The LOINC Table, LOINC Table Core are copyright © 1995-2019, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license.

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