Rickettsia (Typhus Fever) Antibodies (IgG, IgM) with Reflex to Titers

Rickettsia (Typhus Fever) Antibodies (IgG, IgM) with Reflex to Titers

Test Code

37503

CPT Code(s)

86757 (x2)

Test Code

37503

CPT Code(s)

86757 (x2)

In-home collection may be available in your area for purchase through Quest Mobile.

Clinical Significance

Rickettsia (Typhus Fever) Antibodies (IgG, IgM) with Reflex to Titers - Antigen specific IgG and IgM titers allow rapid diagnosis of infection by one or more of the typhus fever group of rickettsial agents. This group includes Rickettsia typhi (endemic or murine typhus) R. prowazeki (epidemic typhus), and Brill-Zinsser disease caused by reactivation of latent R. prowazeki.

Test Resources

Algorithm

An Approach to the Differential Diagnosis of Tick-borne Diseases

Topic Brief

Tick-borne Disease: Laboratory Support of Diagnosis and Management

Test Details

Includes

If R. typhi IgG is Detected, then R. typhi IgG Titer will be performed at an additional charge (CPT code(s): 86317).
If R. typhi IgM is Detected, then R. typhi IgM Titer will be performed at an additional charge (CPT code(s): 86317).

Methodology

Immunofluorescent Assay (IFA)

Reference Range(s)

	Screen	Titer
R. typhi IgG	Not detected	<1:64
R. typhi IgM	Not detected	<1:64

Alternative Name(s)

Weil-Felix,Proteus OX-19,Febrile Agglutinins,Typhus Fever,Proteus OX-2,Proteus OX-K,Endemic Typhus

LOINC® Codes, Performing Laboratory

Service Area must be determined

Includes

If R. typhi IgG is Detected, then R. typhi IgG Titer will be performed at an additional charge (CPT code(s): 86317).
If R. typhi IgM is Detected, then R. typhi IgM Titer will be performed at an additional charge (CPT code(s): 86317).

Methodology

Immunofluorescent Assay (IFA)

Reference Range(s)

	Screen	Titer
R. typhi IgG	Not detected	<1:64
R. typhi IgM	Not detected	<1:64

Alternative Name(s)

Weil-Felix,Proteus OX-19,Febrile Agglutinins,Typhus Fever,Proteus OX-2,Proteus OX-K,Endemic Typhus

LOINC® Codes, Performing Laboratory

Service Area must be determined

Preferred Specimen(s)

1 mL serum

Minimum Volume

0.2 mL

Transport Container

Transport tube

Transport Temperature

Room temperature

Specimen Stability

Room temperature: 7 days
Refrigerated: 14 days
Frozen: 30 day

Reject Criteria

Gross hemolysis • Grossly lipemic

Setup Schedule

Service Area must be determined

Preferred Specimen(s)

1 mL serum

Minimum Volume

0.2 mL

Transport Container

Transport tube

Transport Temperature

Room temperature

Specimen Stability

Room temperature: 7 days
Refrigerated: 14 days
Frozen: 30 day

Reject Criteria

Gross hemolysis • Grossly lipemic

Setup Schedule

Service Area must be determined

In-home collection may be available in your area for purchase through Quest Mobile.

Test Details

Clinical Significance

Test Resources

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

The CPT codes provided are based on AMA guidance and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

This material contains content from LOINC® (http://loinc.org). The LOINC Table, LOINC Table Core are copyright © 1995-2019, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license.

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