Creatine Kinase (CK), Total

Test Code

374

CPT Code(s)

82550

Test Code

374

CPT Code(s)

82550

Not offered in Quest Diagnostics Nichols Institute (IFD) – San Juan Capistrano. Please provide SERVICE AREA INFORMATION to find available tests you can order.

In-home collection may be available in your area for purchase through Quest Mobile.

Clinical Significance

Creatine Kinase (CK), Total -

This test measures creatine kinase (CK), an enzyme found primarily in striated muscle and heart tissue, and may be useful in assessing muscle damage.

CK is a dimeric enzyme composed of either 2 B subunits (CK-BB), 2 M subunits (CK-MM), or an M and a B subunit (CK-MB). CK-MM is the primary isoenzyme found in the skeletal muscle and heart tissue. CK-BB is mainly found in the brain and smooth muscle of gastrointestinal tract and urinary bladder. CK-MB is mainly found in the heart with a small amount in skeletal muscle [1]. An elevated level of any isoenzyme results in an elevated total CK ...

Test Resources

Clinical Focus

Autoimmune Rheumatic and Related Diseases

Clinical Focus

Idiopathic Inflammatory Myopathies: Laboratory Support for Diagnosis

Test Details

Methodology

Spectrophotometry (SP)

Reference Range(s)

Age	Male (U/L)	Female (U/L)
0-3 Days	94-810	94-810
4-28 Days	63-383	63-383
1-11 Months	38-331	38-331
1-4 Years	36-323	33-308
5-6 Years	38-369	30-304
7-9 Years	36-337	33-295
10-12 Years	33-333	28-280
13-18 Years	34-344	22-246
19-49 Years	26-366	20-239
50-59 Years	23-325	21-240
60-69 Years	22-308	20-243
70-79 Years	19-278	18-225
>79 Years	17-247	16-215

Alternative Name(s)

CPK

LOINC® Codes, Performing Laboratory

Service Area must be determined

Methodology

Spectrophotometry (SP)

Reference Range(s)

Age	Male (U/L)	Female (U/L)
0-3 Days	94-810	94-810
4-28 Days	63-383	63-383
1-11 Months	38-331	38-331
1-4 Years	36-323	33-308
5-6 Years	38-369	30-304
7-9 Years	36-337	33-295
10-12 Years	33-333	28-280
13-18 Years	34-344	22-246
19-49 Years	26-366	20-239
50-59 Years	23-325	21-240
60-69 Years	22-308	20-243
70-79 Years	19-278	18-225
>79 Years	17-247	16-215

Alternative Name(s)

CPK

LOINC® Codes, Performing Laboratory

Service Area must be determined

Preferred Specimen(s)

1 mL serum

Alternative Specimen(s)

Plasma collected in: Sodium heparin (green-top) or lithium heparin (green-top) tube

Minimum Volume

0.5 mL

Collection Instructions

If CK and CK Isoenzymes are ordered together, specimen must be submitted frozen

Transport Container

Serum separator tube (SST)

Transport Temperature

Room temperature

Reject Criteria

Gross hemolysis • Anticoagulants other than heparin

Setup Schedule, Specimen Stability

Service Area must be determined

Preferred Specimen(s)

1 mL serum

Alternative Specimen(s)

Plasma collected in: Sodium heparin (green-top) or lithium heparin (green-top) tube

Minimum Volume

0.5 mL

Collection Instructions

If CK and CK Isoenzymes are ordered together, specimen must be submitted frozen

Transport Container

Serum separator tube (SST)

Transport Temperature

Room temperature

Reject Criteria

Gross hemolysis • Anticoagulants other than heparin

Setup Schedule, Specimen Stability

Service Area must be determined

Not offered in Quest Diagnostics Nichols Institute (IFD) – San Juan Capistrano. Please provide SERVICE AREA INFORMATION to find available tests you can order.

In-home collection may be available in your area for purchase through Quest Mobile.

Test Details

Clinical Significance

Test Resources

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

The CPT codes provided are based on AMA guidance and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

This material contains content from LOINC® (http://loinc.org). The LOINC Table, LOINC Table Core are copyright © 1995-2019, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license.

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