B-Type Natriuretic Peptide (BNP)
Test Code
Clinical Significance
B-Type Natriuretic Peptide (BNP) - BNP is increased in congestive heart failure, left ventricular hypertrophy, acute myocardial infarction, coronary angioplasty, and hypertension. Elevations are also observed in pulmonary hypertension (indicating right ventricular dysfunction), acute lung injury, hypervolemic states, chronic renal failure and cirrhosis. Decreasing levels indicate therapeutic response to anti-hypertensive therapy.
Test Resources
Test FAQ
B-Type Natriuretic Peptide (BNP)Test Details
Methodology
Reference Range(s)
Alternative Name(s)
Preferred Specimen(s)
1 mL frozen plasma collected in an EDTA (lavender-top) tube
Minimum Volume
0.5 mL
Collection Instructions
Collect specimen in a plastic EDTA (lavender-top) tube. Centrifuge tube and separate plasma into a plastic specimen transport tube within 1 hour. Freeze plasma immediately.
Note: BNP is unstable in glass containers. Use of glass tubes and glass transfer pipettes will affect accurate quantitation of BNP.
Transport Container
Transport tube
Transport Temperature
Frozen
Specimen Stability
- Room temperature: 1 hour
- Refrigerated: 1 hour
- Frozen: 9 months
Reject Criteria
Collected in a glass tube • PPT potassium EDTA (white-top) tube
Setup Schedule
Note: BNP is unstable in glass containers. Use of glass tubes and glass transfer pipettes will affect accurate quantitation of BNP.
Refrigerated: 1 hour
Frozen: 9 months