B-Type Natriuretic Peptide (BNP)

B-Type Natriuretic Peptide (BNP)

Test Code

37386
83880
CPT Code is subject to a Medicare Limited Coverage Policy and may require a signed ABN when ordering.
37386
83880
CPT Code is subject to a Medicare Limited Coverage Policy and may require a signed ABN when ordering.
Not offered in Quest Diagnostics Nichols Institute (IFD) – San Juan Capistrano. Please provide SERVICE AREA INFORMATION to find available tests you can order.
In-home collection is not available in your area through Quest Mobile.

Clinical Significance

B-Type Natriuretic Peptide (BNP) - BNP is increased in congestive heart failure, left ventricular hypertrophy, acute myocardial infarction, coronary angioplasty, and hypertension. Elevations are also observed in pulmonary hypertension (indicating right ventricular dysfunction), acute lung injury, hypervolemic states, chronic renal failure and cirrhosis. Decreasing levels indicate therapeutic response to anti-hypertensive therapy.

Test Details

Methodology

Immunoassay (IA)

Reference Range(s)

<100 pg/mL

Alternative Name(s)

Brain Natriuretic Peptide,BNP

LOINC® Codes, Performing Laboratory

Methodology

Immunoassay (IA)

Reference Range(s)

<100 pg/mL

Alternative Name(s)

Brain Natriuretic Peptide,BNP

Preferred Specimen(s)

1 mL frozen plasma collected in an EDTA (lavender-top) tube

Minimum Volume

0.5 mL

Collection Instructions

Collect specimen in a plastic EDTA (lavender-top) tube. Centrifuge tube and separate plasma into a plastic specimen transport tube within 1 hour. Freeze plasma immediately.

Note: BNP is unstable in glass containers. Use of glass tubes and glass transfer pipettes will affect accurate quantitation of BNP.

Transport Container

Transport tube

Transport Temperature

Frozen

Specimen Stability

  • Room temperature: 1 hour
  • Refrigerated: 1 hour
  • Frozen: 9 months

Reject Criteria

Collected in a glass tube • PPT potassium EDTA (white-top) tube

Setup Schedule

1 mL frozen plasma collected in an EDTA (lavender-top) tube
0.5 mL
Collect specimen in a plastic EDTA (lavender-top) tube. Centrifuge tube and separate plasma into a plastic specimen transport tube within 1 hour. Freeze plasma immediately.

Note: BNP is unstable in glass containers. Use of glass tubes and glass transfer pipettes will affect accurate quantitation of BNP.
Transport tube
Frozen
Room temperature: 1 hour
Refrigerated: 1 hour
Frozen: 9 months
Collected in a glass tube • PPT potassium EDTA (white-top) tube
Not offered in Quest Diagnostics Nichols Institute (IFD) – San Juan Capistrano. Please provide SERVICE AREA INFORMATION to find available tests you can order.
In-home collection is not available in your area through Quest Mobile.
Test Details

Clinical Significance

Test Resources

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

The CPT codes provided are based on AMA guidance and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

This material contains content from LOINC® (http://loinc.org). The LOINC Table, LOINC Table Core are copyright © 1995-2019, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license.

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