Estrone Sulfate

Estrone Sulfate

Test Code

37104
82679
37104
82679
Not offered in Quest Diagnostics Nichols Institute (IFD) – San Juan Capistrano. Please provide SERVICE AREA INFORMATION to find available tests you can order.
In-home collection may be available in your area for purchase through Quest Mobile.

Clinical Significance

Estrone Sulfate -

This test measures serum concentration of estrone sulfate, an endogenous estrogen that can convert to estrone and estradiol. Estrone sulfate has been investigated as a potential biomarker for several estrogen-associated malignancies, such as breast cancer, endometrial cancer, ovarian cancer, and prostate cancer [1].

Estrone sulfate is the most abundant circulating estrogen in nonpregnant persons. Although biologically inactive, estrone sulfate is a precursor of estrone, which can be converted to estradiol, the most potent estrogen in nonpregnant persons. In children, men, and postmenopausal ...

Test Resources

None found for this test
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Test Details

Methodology

Chromatography/Mass Spectrometry

Assay Category

This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Reference Range(s)

Adult Males231-2125 pg/mL
Females, premenopausal 
  Follicular Phase192-2950 pg/mL
  Luteal phase282-5049 pg/mL
Females, postmenopausal42-846 pg/mL

LOINC® Codes, Performing Laboratory

Methodology

Chromatography/Mass Spectrometry
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Reference Range(s)

Adult Males231-2125 pg/mL
Females, premenopausal 
  Follicular Phase192-2950 pg/mL
  Luteal phase282-5049 pg/mL
Females, postmenopausal42-846 pg/mL

Preferred Specimen(s)

0.5 mL serum

Alternative Specimen(s)

Plasma collected in: EDTA (lavender-top) tube

Minimum Volume

0.3 mL

Transport Container

Transport tube

Transport Temperature

Refrigerated (cold packs)

Specimen Stability

  • Room temperature: 5 days
  • Refrigerated: 21 days
  • Frozen -20° C: 1 year
  • Frozen -70° C: 1 year

Reject Criteria

Moderate to gross hemolysis • Grossly lipemic

Setup Schedule

0.5 mL serum
Plasma collected in: EDTA (lavender-top) tube
0.3 mL
Transport tube
Refrigerated (cold packs)
Room temperature: 5 days
Refrigerated: 21 days
Frozen -20° C: 1 year
Frozen -70° C: 1 year
Moderate to gross hemolysis • Grossly lipemic
Not offered in Quest Diagnostics Nichols Institute (IFD) – San Juan Capistrano. Please provide SERVICE AREA INFORMATION to find available tests you can order.
In-home collection may be available in your area for purchase through Quest Mobile.
Test Details

Clinical Significance

Test Resources

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

The CPT codes provided are based on AMA guidance and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

This material contains content from LOINC® (http://loinc.org). The LOINC Table, LOINC Table Core are copyright © 1995-2019, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license.

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