Estrone Sulfate
Test Code
Clinical Significance
Estrone Sulfate -
This test measures serum concentration of estrone sulfate, an endogenous estrogen that can convert to estrone and estradiol. Estrone sulfate has been investigated as a potential biomarker for several estrogen-associated malignancies, such as breast cancer, endometrial cancer, ovarian cancer, and prostate cancer [1].
Estrone sulfate is the most abundant circulating estrogen in nonpregnant persons. Although biologically inactive, estrone sulfate is a precursor of estrone, which can be converted to estradiol, the most potent estrogen in nonpregnant persons. In children, men, and postmenopausal ...
Test Resources
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Test Details
Methodology
Reference Range(s)
| Adult Males | 231-2125 pg/mL |
| Females, premenopausal | |
| Follicular Phase | 192-2950 pg/mL |
| Luteal phase | 282-5049 pg/mL |
| Females, postmenopausal | 42-846 pg/mL |
Preferred Specimen(s)
0.5 mL serum
Alternative Specimen(s)
Plasma collected in: EDTA (lavender-top) tube
Minimum Volume
0.3 mL
Transport Container
Transport tube
Transport Temperature
Refrigerated (cold packs)
Specimen Stability
- Room temperature: 5 days
- Refrigerated: 21 days
- Frozen -20° C: 1 year
- Frozen -70° C: 1 year
Reject Criteria
Moderate to gross hemolysis • Grossly lipemic
Setup Schedule
Refrigerated: 21 days
Frozen -20° C: 1 year
Frozen -70° C: 1 year