Cortisone, Serum

Test Code

37098

CPT Code(s)

82542

Test Code

37098

CPT Code(s)

82542

Not offered in Quest Diagnostics Nichols Institute (IFD) – San Juan Capistrano. Please provide SERVICE AREA INFORMATION to find available tests you can order.

In-home collection may be available in your area for purchase through Quest Mobile.

Clinical Significance

Cortisone, Serum - Measurement of both Free Cortisol and Cortisone are useful in diagnosing patients with low-renin hypertension caused by apparent mineralocorticoid excess. This may be due to either an inherited defect in 11HSDB2 enzyme or an acquired inhibitor of the enzyme by such compounds as glycyrrhizic acid, a component of natural licorice.

Test Resources

None found for this test
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Test Details

Patient Preparation

Overnight fasting is preferred

Methodology

Chromatography/Mass Spectrometry

Assay Category

This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Reference Range(s)

	AM (mcg/dL)	PM (mcg/dL)
Adult Males and Females	1.2-3.5	0.6-2.8

	AM (mcg/dL)
Full Term Infants, birth**	2.6-15.6
7 Days**	0.3-4.5
2 Weeks-3 Months**	0.9-5.4
4-11 Months	0.5-4.1
1 Year	0.5-4.0
2-3 Years	0.5-3.9
4 Years	0.5-4.0
5 Years	0.5-4.1
6 Years	0.6-4.3
7 Years	0.7-4.5
8 Years	0.8-4.7
9 Years	0.9-4.9
10 Years	0.9-5.1
11-12 Years	1.0-5.2
13-17 Years	1.0-5.3

Pediatric lower reference values are reflective of both AM and early PM sampling

**Pediatric data from Sippell WG et al., Pediat Res (1980) 14:39-46.

LOINC® Codes, Performing Laboratory

Service Area must be determined

Patient Preparation

Overnight fasting is preferred

Methodology

Chromatography/Mass Spectrometry

Assay Category

Reference Range(s)

	AM (mcg/dL)	PM (mcg/dL)
Adult Males and Females	1.2-3.5	0.6-2.8

	AM (mcg/dL)
Full Term Infants, birth**	2.6-15.6
7 Days**	0.3-4.5
2 Weeks-3 Months**	0.9-5.4
4-11 Months	0.5-4.1
1 Year	0.5-4.0
2-3 Years	0.5-3.9
4 Years	0.5-4.0
5 Years	0.5-4.1
6 Years	0.6-4.3
7 Years	0.7-4.5
8 Years	0.8-4.7
9 Years	0.9-4.9
10 Years	0.9-5.1
11-12 Years	1.0-5.2
13-17 Years	1.0-5.3

Pediatric lower reference values are reflective of both AM and early PM sampling

**Pediatric data from Sippell WG et al., Pediat Res (1980) 14:39-46.

LOINC® Codes, Performing Laboratory

Service Area must be determined

Preferred Specimen(s)

1 mL serum collected in a red-top tube (no gel)

Alternative Specimen(s)

Plasma collected in: EDTA (lavender-top) tube

Minimum Volume

0.3 mL

Collection Instructions

Specify time of day specimen was collected

Transport Container

Transport tube

Transport Temperature

Refrigerated (cold packs)

Specimen Stability

Room temperature: 48 hours
Refrigerated: 21 days
Frozen: 1 year

Reject Criteria

Gross hemolysis • Received room temperature • Serum separator tube (SST)

Setup Schedule

Service Area must be determined

Preferred Specimen(s)

1 mL serum collected in a red-top tube (no gel)

Alternative Specimen(s)

Plasma collected in: EDTA (lavender-top) tube

Minimum Volume

0.3 mL

Collection Instructions

Specify time of day specimen was collected

Transport Container

Transport tube

Transport Temperature

Refrigerated (cold packs)

Specimen Stability

Room temperature: 48 hours
Refrigerated: 21 days
Frozen: 1 year

Reject Criteria

Gross hemolysis • Received room temperature • Serum separator tube (SST)

Setup Schedule

Service Area must be determined

Not offered in Quest Diagnostics Nichols Institute (IFD) – San Juan Capistrano. Please provide SERVICE AREA INFORMATION to find available tests you can order.

In-home collection may be available in your area for purchase through Quest Mobile.

Test Details

Clinical Significance

Test Resources

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

The CPT codes provided are based on AMA guidance and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

This material contains content from LOINC® (http://loinc.org). The LOINC Table, LOINC Table Core are copyright © 1995-2019, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license.

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