Natural Killer Cells

Test Code

37088

CPT Code(s)

86357

CPT Code is subject to a Medicare Limited Coverage Policy and may require a signed ABN when ordering.

Test Code

37088

CPT Code(s)

86357

CPT Code is subject to a Medicare Limited Coverage Policy and may require a signed ABN when ordering.

In-home collection may be available in your area for purchase through Quest Mobile.

Clinical Significance

Natural Killer Cells - Low numbers of NK cells are found in individuals who are susceptible to viral infections, including cytomegalovirus and varicella.

Test Resources

None found for this test
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Test Details

Includes

Absolute Lymphocytes
NK Cells CD3-CD16+CD56+ABS
CD3-/CD16+CD56+(%)

Methodology

Flow Cytometry (FC)

Reference Range(s)

Absolute Lymphocytes
3 days	2000-11500 cells/uL
2 weeks	2000-17000 cells/uL
1 month	2500-16500 cells/uL
2 months	3300-15000 cells/uL
6 months	4000-13500 cells/uL
2 years	4000-10500 cells/uL
6 years	2000-8000 cells/uL
12 years	1500-6500 cells/uL
18 years	1200-5200 cells/uL
>18 years	850-3900 cells/uL

Natural Killer Cells CD3-CD16+CD56+ (ABS)
1 year	160-930 cells/uL
2 years	95-620 cells/uL
6 years	60-540 cells/uL
12 years	70-500 cells/uL
18 years	60-430 cells/uL
>18 years	70-760 cells/uL

CD3-/CD16+CD56+ (%)
1 year	3-14 %
2 years	2-16 %
6 years	3-20 %
12 years	3-19 %
18 years	3-18 %
>18 years	4-25 %

LOINC® Codes, Performing Laboratory

Service Area must be determined

Includes

Absolute Lymphocytes
NK Cells CD3-CD16+CD56+ABS
CD3-/CD16+CD56+(%)

Methodology

Flow Cytometry (FC)

Reference Range(s)

Absolute Lymphocytes
3 days	2000-11500 cells/uL
2 weeks	2000-17000 cells/uL
1 month	2500-16500 cells/uL
2 months	3300-15000 cells/uL
6 months	4000-13500 cells/uL
2 years	4000-10500 cells/uL
6 years	2000-8000 cells/uL
12 years	1500-6500 cells/uL
18 years	1200-5200 cells/uL
>18 years	850-3900 cells/uL

Natural Killer Cells CD3-CD16+CD56+ (ABS)
1 year	160-930 cells/uL
2 years	95-620 cells/uL
6 years	60-540 cells/uL
12 years	70-500 cells/uL
18 years	60-430 cells/uL
>18 years	70-760 cells/uL

CD3-/CD16+CD56+ (%)
1 year	3-14 %
2 years	2-16 %
6 years	3-20 %
12 years	3-19 %
18 years	3-18 %
>18 years	4-25 %

LOINC® Codes, Performing Laboratory

Service Area must be determined

Preferred Specimen(s)

5 mL whole blood collected in an EDTA (lavender-top) tube

Minimum Volume

0.5 mL

Collection Instructions

Do not freeze. Do not transfer whole blood to M4. Submit EDTA tube at room temperature.

Transport Container

EDTA (lavender-top) tube

Transport Temperature

Room temperature

Specimen Stability

Room temperature: 72 hours
Refrigerated: Unacceptable
Frozen: Unacceptable

Reject Criteria

Hemolysis • Received refrigerated • Received frozen

Setup Schedule

Service Area must be determined

Preferred Specimen(s)

5 mL whole blood collected in an EDTA (lavender-top) tube

Minimum Volume

0.5 mL

Collection Instructions

Do not freeze. Do not transfer whole blood to M4. Submit EDTA tube at room temperature.

Transport Container

EDTA (lavender-top) tube

Transport Temperature

Room temperature

Specimen Stability

Room temperature: 72 hours
Refrigerated: Unacceptable
Frozen: Unacceptable

Reject Criteria

Hemolysis • Received refrigerated • Received frozen

Setup Schedule

Service Area must be determined

In-home collection may be available in your area for purchase through Quest Mobile.

Test Details

Clinical Significance

Test Resources

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

The CPT codes provided are based on AMA guidance and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

This material contains content from LOINC® (http://loinc.org). The LOINC Table, LOINC Table Core are copyright © 1995-2019, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license.

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