Cytomegalovirus DNA, Quantitative Real-Time PCR, Saliva
Test Code
Clinical Significance
Cytomegalovirus DNA, Quantitative Real-Time PCR, Saliva - Cytomegalovirus (CMV) is the most common congenital infection in newborns, and a leading cause of non-genetic hearing loss and other neurologic complications including microcephaly, developmental delay, and vision impairment.
Most infants with congenital CMV (cCMV) infection are asymptomatic at birth. Symptomatic neonates born with hepatosplenomegaly, hepatitis, thrombocytopenia, structural brain malformations, and other abnormalities are recognized and provided appropriate medical care, but asymptomatic infants appear normal at birth, so miss the opportunity for early diagnosis ...
Test Resources
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Test Details
Methodology
Reference Range(s)
| CMV DNA, QN, PCR | Not detected (IU/mL) |
| CMV DNA, QN, PCR | Not detected (Log IU/mL) |
Alternative Name(s)
Preferred Specimen(s)
Saliva collected in an ORACollection OCDC-100 collection device
Minimum Volume
One ORACollection OCDC-100 collection device
Collection Instructions
Precaution: Saliva samples should be collected at least 30 minutes after eating or drinking.
Ensure the sponge tip does not come into contact with any surface prior to collection.
Collection procedure
1. Open package and remove collector without touching sponge tip. Place the saliva sponge into the child's mouth in the cheek pouch (the space between the gums and the inner cheek).
2. Gently move the saliva sponge around the upper and lower cheek pouches on both sides of the mouth to soak up as much saliva as possible. There is no need to 'scrape' the inner cheek with saliva sponge - collect as much saliva as possible from the cheek pouches. The sponge will absorb more saliva if it is left in the child's mouth for a longer time (up to 60 seconds).
3. Once collected, hold the tube upright to prevent stabilizing liquid inside the tube from spilling. Unscrew the blue cap from the collection tube without touching the sponge.
4. Insert the sponge into the tube and close cap tightly.
5. Invert the capped tube and shake vigorously 10 times.
Transport Container
ORACollection OCDC-100 collection device
Transport Temperature
Refrigerated (cold packs)
Specimen Stability
- Room temperature: 48 hours
- Refrigerated: 14 days
- Frozen: 30 days
Reject Criteria
Specimen sources other than saliva submitted in ORACollection OCDC-100 collection device • Saliva specimens not received in ORACollection OCDC-100 collection device
Setup Schedule
Ensure the sponge tip does not come into contact with any surface prior to collection.
Collection procedure
1. Open package and remove collector without touching sponge tip. Place the saliva sponge into the child's mouth in the cheek pouch (the space between the gums and the inner cheek).
2. Gently move the saliva sponge around the upper and lower cheek pouches on both sides of the mouth to soak up as much saliva as possible. There is no need to 'scrape' the inner cheek with saliva sponge - collect as much saliva as possible from the cheek pouches. The sponge will absorb more saliva if it is left in the child's mouth for a longer time (up to 60 seconds).
3. Once collected, hold the tube upright to prevent stabilizing liquid inside the tube from spilling. Unscrew the blue cap from the collection tube without touching the sponge.
4. Insert the sponge into the tube and close cap tightly.
5. Invert the capped tube and shake vigorously 10 times.
Refrigerated: 14 days
Frozen: 30 days