Childhood and Tree Nut Allergy Panel with Reflex to Components

Test code

36766

CPT code(s)*

86003 (x21), 82785

**CPT Code is subject to a Medicare Limited Coverage Policy and may require a signed ABN when ordering.

In-home collection may be available in your area for purchase through Quest Mobile.

Clinical significance

Childhood and Tree Nut Allergy Panel with Reflex to Components - Up to 90 percent of children with asthma have underlying allergies that trigger their asthma [1,2]. Many things like environmental and food elements can trigger allergic reactions in children. Specific IgE serological tests aid in the diagnosis of allergic disease. In this profile, when a whole allergen protein extract is found to be positive, the respective component panel, which uses individual recombinant or purified proteins, is automatically run. Component panels improve specificity, provide the clinician with more detailed information for assessing level of risk, and help target effective management.1. Allen-Ramey F,…

Test resources

Topic brief

Component Testing for Food Allergy

Component Testing for Furry Pet Allergies

Details

Test details

The information below details the components of this test. For overall setup schedule, see Performing lab & setup schedule.

Included components

Test code	Test name	Orderable separately	Setup schedule
2820	Almond (f20) IgE	Yes	Set up: Mon-Sat (All shifts); Report available: 1 day
2706	Alternaria alternata (m6) IgE	Yes	Set up: Mon-Sat (All shifts); Report available: 1 day
94464	Brazil Nut (f18) IgE with Reflex to Component	Yes	Set up: Mon-Sat (All shifts); Report available: 1 day
94465	Cashew Nut (f202) IgE with Reflex to Component	Yes	Set up: Mon-Sat (All shifts); Report available: 2 days
10564	Cat Dander (e1) IgE with Reflex to Component Panel	Yes	Set up: Mon-Sat; Report available: 1 day
2702	Cladosporium herbarum (m2) IgE	Yes	Set up: Mon-Sat (All shifts); Report available: 1 day
2736	Cockroach (i6) IgE	Yes	Set up: Mon-Sat (All shifts); Report available: 1 day
2803	Codfish (f3) IgE	Yes	Set up: Mon-Sat (All shifts); Report available: 1 day
37900	Cow's Milk (f2) IgE with Reflex to Milk Component Panel	Yes	Set up: Mon-Sat (Day shift); Report available: 1 day
2722	Dermatophagoides farinae (d2) IgE	Yes	Set up: Mon-Sat (All shifts); Report available: 1 day
2721	Dermatophagoides pteronyssinus (d1) IgE	Yes	Set up: Mon-Sat (All shifts); Report available: 1 day
10571	Dog Dander (e5) IgE with Reflex to Component Panel	Yes	Set up: Mon-Sat; Report available: 1 day
37906	Egg White (f1) IgE with Reflex to Egg Component Panel	Yes	Set up: Mon-Sat (Day shift); Report available: 1 day
94468	Hazelnut (f17) IgE with Reflex to Component Panel	Yes	Set up: Mon-Sat (All shifts); Report available: 1 day
542	IgE	Yes	Set up: Tues-Sat (All shifts); Report available: 3 days
38475	Macadamia Nut (rf345) IgE	Yes	Set up: Mon-Sat (All shifts); Report available: 2 days
2658	Mouse Urine Proteins (e72) IgE	Yes	Set up: Mon-Sat (All shifts); Report available: 1 day
91747	Peanut, Total with Reflex to Peanut Component Panel	Yes	Set up: Mon-Sat (All shifts); Report available: 1 day
2824	Shrimp (f24) IgE	Yes	Set up: Mon-Sat (All shifts); Report available: 1 day
2814	Soybean (f14) IgE	Yes	Set up: Mon-Sat (All shifts); Report available: 1 day
94467	Walnut (f256) IgE with Reflex to Component Panel	Yes	Set up: Mon-Sat (All shifts); Report available: 2 days
2804	Wheat (f4) IgE	Yes	Set up: Mon-Sat (All shifts); Report available: 1 day

Includes

IgE allergy testing for:
Almond (f20)
Alternaria alternata (m6)
Brazil Nut (f18) IgE with Reflex to Component
Cashew Nut (f202) IgE with Reflex to Component
Cat Dander (e1) IgE with Reflex to Component Panel
Cladosporium herbarum (m2)
Cockroach (i6)
Codfish (f3)
Cow's Milk (f2) IgE with Reflex to Milk Component Panel
Dermatophagoides farinae (d2)
Dermatophagoides pteronyssinus (d1)
Dog Dander (e5) IgE with Reflex to Component Panel
Egg White (f1) IgE with Reflex to Egg Component Panel
Hazelnut (f17) IgE with Reflex to Component Panel
Macadamia Nut (rf345)
Mouse Urine Proteins (e72)
Peanut, Total with Reflex to Peanut Component Panel
Shrimp (f24)
Soybean (f14)
Walnut (f256) IgE with Reflex to Component Panel
Wheat (f4)

Immunoglobulin E

If Brazil Nut (f18) IgE is ≥0.10 kU/L, then Brazil Nut Component Ber e1 (f354) will be performed at an additional charge (CPT code(s): 86008).

If Cashew Nut (f202) IgE is ≥0.10 kU/L, then Cashew Nut Component Ana o3 (f443) will be performed at an additional charge (CPT code(s): 86008).

If Cat Dander (e1) IgE is ≥0.10 kU/L, then Cat Component Panel will be performed at an additional charge (CPT code(s): 86008 (x4)).
Cat Dander Component Panel includes Fel d 1 (e94) IgE, Fel d 2 (e220) IgE, Fel d 4 (e228) IgE, Fel d 7, and (e231) IgE.

If Cow's Milk (f2) IgE is ≥0.10 kU/L, then Milk Component Panel will be performed at an additional charge (CPT code(s): 86008 x3).
Milk Component Panel includes Alpha-lactalbumin (f76) IgE, Beta-lactoglobulin (f77) IgE, and Casein (f78) IgE.

If Dog Dander (e5) IgE is ≥0.10 kU/L, then Dog Component Panel will be performed at an additional charge (CPT code(s): 86008 (x6)).
Dog Dander Component Panel includes Can f 1 (e101) IgE, Can f 2 (e102) IgE, Can f 3 (e221) IgE, Can f 4 (e229) IgE, Can f 5 (e226) IgE, and Can f 6 (e230) IgE.

If Egg White (f1) IgE is ≥0.10 kU/L, then Egg Component Panel will be performed at an additional charge (CPT code(s): 86008 x2).
Egg Component Panel includes Ovalbumin (f232) IgE and Ovomucoid (f233) IgE.

If Hazelnut (f17) IgE is ≥0.10 kU/L, then Hazelnut Component Panel will be performed at an additional charge (CPT code(s): 86008 x4).
Hazelnut Component Panel includes Cor a1 (f428), Cor a8 (f425), Cor a9 (f440), and Cor a14 (f439).

If Peanut (f13) IgE is ≥0.10 kU/L, then Peanut Component Panel will be performed at an additional charge (CPT code(s): 86008 x6).
Peanut Component Panel includes Ara h 1 (f422), Ara h 2 (f423), Ara h 3 (f424), Ara h 6 (f447), Ara h 8 (f352), and Ara h 9 (f427).

If Walnut (f256) IgE is ≥0.10 kU/L, then Walnut Component Panel will be performed at an additional charge (CPT code(s): 86008 x2).
Walnut Component Panel includes rJug r1(f441) and rJug r3 (f442).

Methodology

Immunoassay (IA)

Alternative name(s)

Tree Nut Childhood Allergy,ImmunoCAP®

Specimen requirements
Patient preparation	None Specified
Preferred specimen(s)	5 mL serum
Minimum volume	3.5 mL
Transport container	Serum separator tube (SST)
Transport temperature	Room temperature
Specimen stability	Room temperature: 14 days Refrigerated: 14 days Frozen: 30 days

Reflex tests

Test 36766 is orderable without reflexes as: 36765 - Childhood and Tree Nut Allergy Panel

Test code	Test name	Orderable separately	Reflex criteria
%94469	BRAZIL NUT COMPONENT	No	If Brazil Nut (f18) IgE is ≥0.10 kU/L, then Brazil Nut Component will be performed.
%94470	CASHEW NUT COMPONENT	No	If Cashew Nut (f202) IgE is ≥0.10 kU/L, then Cashew Nut Component will be performed.
%10558	CAT DANDER COMPONENT PANEL	No	If Cat Dander (e1) IgE is ≥0.10 kU/L, then Cat Component Panel will be performed.
%91403	MILK COMPONENT PANEL	No	If Cow's Milk (f2) IgE is ≥0.10 kU/L, then Milk Component Panel will be performed.
%10569	DOG DANDER COMPONENT PANEL	No	If Dog Dander (e5) IgE is ≥0.10 kU/L, then Dog Component Panel will be performed.
%91372	EGG COMPONENT PANEL	No	If Egg White (f1) IgE is ≥0.10 kU/L, then Egg Component Panel will be performed.
%94476	HAZELNUT COMPONENT PANEL	No	If Hazelnut (f17) IgE is ≥0.10 kU/L, then Hazelnut Component Panel will be performed.
%91681	PEANUT COMPONENT PANEL	No	If Peanut (f13) IgE is ≥0.10 kU/L, then Peanut Component Panel will be performed.
%94472	WALNUT COMPONENT PANEL	No	If Walnut (f256) IgE is ≥0.10 kU/L, then Walnut Component Panel will be performed.

Reference range(s)

See Laboratory Report

LOINC® codes

The Result and LOINC® information listed below should not be used for electronic interface maintenance with Quest Diagnostics. Please contact the Quest Diagnostics Connectivity Help Desk for more information at 800-697-9302.

NOTE: The codes listed in the table are not orderable Test Codes

Result code	Result name	LOINC code	Component name
55020300	IMMUNOGLOBULIN E	19113-0	IgE
55083605	PEANUT (F13) IGE	6206-7	Arachis hypogaea Ab.IgE
55083610	CLASS	102501-4	Arachis hypogaea Ab.IgE
55083705	ALMOND (F20) IGE	6019-4	Prunus dulcis Ab.IgE
55083710	CLASS	102133-6	Prunus dulcis Ab.IgE
55084505	CODFISH (F3) IGE	6082-2	Gadus morhua Ab.IgE
55084510	CLASS	102247-4	Gadus morhua Ab.IgE
55084705	SHRIMP (F24) IGE	6246-3	Pandalus borealis Ab.IgE
55084710	CLASS	102594-9	Pandalus borealis Ab.IgE
55084775	MACADAMIA NUT (RF345) IGE **	11183-1	Macadamia spp Ab.IgE
55084780	CLASS	102766-3	Macadamia spp Ab.IgE
55085805	EGG WHITE (F1) IGE	6106-9	Egg white Ab.IgE
55085810	CLASS	102286-2	Egg white Ab.IgE
55085905	COW'S MILK (F2) IGE	6174-7	Milk Ab.IgE
55085910	CLASS	102438-9	Milk Ab.IgE
55086005	WHEAT (F4) IGE	6276-0	Triticum aestivum Ab.IgE
55086010	CLASS	102656-6	Triticum aestivum Ab.IgE
55086205	SOYBEAN (F14) IGE	6248-9	Glycine max Ab.IgE
55086210	CLASS	102172-4	Glycine max Ab.IgE
55090005	DERMATOPHAGOIDES PTERONYSSINUS (D1) IGE	6096-2	Dermatophagoides pteronyssinus Ab.IgE
55090010	CLASS	102279-7	Dermatophagoides pteronyssinus Ab.IgE
55094405	DERMATOPHAGOIDES FARINAE (D2) IGE	6095-4	Dermatophagoides farinae Ab.IgE
55094410	CLASS	102277-1	Dermatophagoides farinae Ab.IgE
55094505	CAT DANDER (E1) IGE	6833-8	Cat dander Ab.IgE
55094510	CLASS	102210-2	Cat dander Ab.IgE
55094605	DOG DANDER (E5) IGE	6098-8	Dog dander Ab.IgE
55094610	CLASS	102282-1	Dog dander Ab.IgE
55094905	CLADOSPORIUM HERBARUM (M2) IGE	6075-6	Cladosporium herbarum Ab.IgE
55094910	CLASS	102240-9	Cladosporium herbarum Ab.IgE
55095005	ALTERNARIA ALTERNATA (M6) IGE	6020-2	Alternaria alternata Ab.IgE
55095010	CLASS	102136-9	Alternaria alternata Ab.IgE
55098105	MOUSE URINE PROTEINS (E72) IGE	6181-2	Mouse urine proteins Ab.IgE
55098110	CLASS	102453-8	Mouse urine proteins Ab.IgE
55099505	COCKROACH (I6) IGE	6078-0	Blatella germanica Ab.IgE
55099510	CLASS	102245-8	Blatella germanica Ab.IgE
55107005	HAZELNUT (F17) IGE	6136-6	Corylus avellana Ab.IgE
55107010	CLASS	102361-3	Corylus avellana Ab.IgE
55107105	BRAZIL NUT (F18) IGE	6050-9	Bertholletia excelsa Ab.IgE
55107110	CLASS	102189-8	Bertholletia excelsa Ab.IgE
55168205	CASHEW NUT (F202) IGE	6718-1	Anacardium occidentale Ab.IgE
55168210	CLASS	102209-4	Anacardium occidentale Ab.IgE
55172005	WALNUT (F256) IGE	6273-7	Juglans spp Ab.IgE
55172010	CLASS	102647-5	Juglans spp Ab.IgE

BRAZIL NUT COMPONENT

Result code	Result name	LOINC code	Component name
86017982	Ber e1 (f354)	64963-2	Bertholletia excelsa recombinant (rBer e) 1 Ab.IgE

CASHEW NUT COMPONENT

Result code	Result name	LOINC code	Component name
86017983	Ana o3 (f443)	82539-8	Anacardium occidentale recombinant (rAna o) 3 Ab.IgE

CAT DANDER COMPONENT PANEL

Result code	Result name	LOINC code	Component name
86032291	Fel d 1 (e94) IgE	64975-6	Cat recombinant (rFel d) 1 Ab.IgE
86032292	Fel d 2 (e220) IgE	19732-7	Cat serum albumin Ab.IgE
86032293	Fel d 4 (e228) IgE	64976-4	Cat recombinant (rFel d) 4 Ab.IgE
86032294	Fel d 7 (e231) IgE	94278-9	Cat recombinant (rFel d) 7 Ab.IgE

MILK COMPONENT PANEL

Result code	Result name	LOINC code	Component name
55087105	CASEIN (F78) IGE	6062-4	Casein Ab.IgE
55087110	CLASS	102208-6	Casein Ab.IgE
55107605	ALPHA-LACTALBUMIN (F76) IGE	7445-0	Lactalbumin alpha Ab.IgE
55107610	CLASS	102135-1	Lactalbumin alpha Ab.IgE
55107705	BETA-LACTOGLOBULIN (F77) IGE	6042-6	Beta lactoglobulin MF77 Ab.IgE
55107710	CLASS	102180-7	Beta lactoglobulin Ab.IgE

DOG DANDER COMPONENT PANEL

Result code	Result name	LOINC code	Component name
86032295	Can f 1 (e101) IgE	58773-3	Dog recombinant (rCan f) 1 Ab.IgE
86032296	Can f 2 (e102) IgE	58772-5	Dog recombinant (rCan f) 2 Ab.IgE
86032297	Can f 3 (e221) IgE	19738-4	Dog serum albumin Ab.IgE
86032298	Can f 4 (e229) IgE	82543-0	Dog recombinant (rCan f) 4 Ab.IgE
86032299	Can f 5 (e226) IgE	64973-1	Dog recombinant (rCan f) 5 Ab.IgE
86032300	Can f 6 (e230) IgE	94277-1	Dog recombinant (rCan f) 6 Ab.IgE

EGG COMPONENT PANEL

Result code	Result name	LOINC code	Component name
55170505	OVALBUMIN (F232) IGE	7556-4	Ovalbumin Ab.IgE
55170510	CLASS	102482-7	Ovalbumin Ab.IgE
55170605	OVOMUCOID (F233) IGE	7557-2	Ovomucoid Ab.IgE
55170610	CLASS	102483-5	Ovomucoid Ab.IgE

HAZELNUT COMPONENT PANEL

Result code	Result name	LOINC code	Component name
86017986	Cor a1 (f428)	69421-6	Corylus avellana recombinant (rCor a) 1 Ab.IgE
86017987	Cor a8 (f425)	58753-5	Corylus avellana recombinant (rCor a) 8 Ab.IgE
86017988	Cor a9 (f440)	65765-0	Corylus avellana native (nCor a) 9 Ab.IgE
86017989	Cor a14 (f439)	81788-2	Corylus avellana recombinant (rCor a) 14 Ab.IgE

PEANUT COMPONENT PANEL

Result code	Result name	LOINC code	Component name
86009798	Ara h 2 (f423)	58778-2	Arachis hypogaea recombinant (rAra h) 2 Ab.IgE
86009799	Ara h 1 (f422)	58779-0	Arachis hypogaea recombinant (rAra h) 1 Ab.IgE
86009800	Ara h 3 (f424)	58777-4	Arachis hypogaea recombinant (rAra h) 3 Ab.IgE
86009801	Ara h 9 (f427)	64965-7	Arachis hypogaea recombinant (rAra h) 9 Ab.IgE
86009802	Ara h 8 (f352)	63477-4	Arachis hypogaea recombinant (rAra h) 8 Ab.IgE
86026753	Ara h 6 (f447)	90880-6	Arachis hypogaea recombinant (rAra h) 6 Ab.IgE

WALNUT COMPONENT PANEL

Result code	Result name	LOINC code	Component name
86017984	rJug r1 (f441)	81790-8	Juglans regia recombinant (rJug r) 1 Ab.IgE
86017985	rJug r3 (f442)	81789-0	Juglans regia recombinant (rJug r) 3 Ab.IgE

Performing lab & setup schedule

Performing laboratory

Quest Diagnostics - East Region

Setup schedule

Information not provided in East (Eastern PA, MD, DE, VA, NY, NJ, Southern CT) – Contact lab or Customer service to determine turnaround time

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

*The CPT codes provided are based on AMA guidance and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

This material contains content from LOINC® (http://loinc.org). The LOINC Table, LOINC Table Core are copyright © 1995-2019, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license.

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