ANCA Vasculitides

Test Code

36733

CPT Code(s)

86021 (x2)

Test Code

36733

CPT Code(s)

86021 (x2)

Not offered in Quest Diagnostics Nichols Institute (IFD) – San Juan Capistrano. Please provide SERVICE AREA INFORMATION to find available tests you can order.

In-home collection may be available in your area for purchase through Quest Mobile.

Clinical Significance

ANCA Vasculitides - Testing for anti-neutrophil cytoplasmic antibodies (P-ANCA and/or C-ANCA) has been found to be useful in establishing the diagnosis of suspected vascular diseases (e.g., crescentic glomerulonephritis, microscopic polyarteritis and Churg-Strauss syndrome), bowel disease (Crohn's Disease, ulcerative colitis, primary sclerosing cholangitis, and autoimmune hepatitis) as well as with other autoimmune diseases (drug-induced lupus, SLE, Felty's syndrome).
ANCA has classically been divided into C-ANCA and P-ANCA depending on the immunofluorescent pattern observed. More recently the specific ...

Test Resources

Clinical Focus

Autoimmune Rheumatic and Related Diseases

Test Details

Includes

Myeloperoxidase Antibody, Proteinase-3 Antibody

Methodology

Immunoassay (IA)

Reference Range(s)

Myeloperoxidase Antibody

<1.0 AI				No antibody detected
≥1.0 AI				Antibody detected

Proteinase-3 Antibody

<1.0 AI				No antibody detected
≥1.0 AI				Antibody detected

Alternative Name(s)

Neutrophil Cytoplasmic Antibodies,ANCA Panel for Vasculitis, Serum

LOINC® Codes, Performing Laboratory

Service Area must be determined

Includes

Myeloperoxidase Antibody, Proteinase-3 Antibody

Methodology

Immunoassay (IA)

Reference Range(s)

Myeloperoxidase Antibody

<1.0 AI				No antibody detected
≥1.0 AI				Antibody detected

Proteinase-3 Antibody

<1.0 AI				No antibody detected
≥1.0 AI				Antibody detected

Alternative Name(s)

Neutrophil Cytoplasmic Antibodies,ANCA Panel for Vasculitis, Serum

LOINC® Codes, Performing Laboratory

Service Area must be determined

Preferred Specimen(s)

1 mL serum

Minimum Volume

0.3 mL

Transport Container

Transport tube

Transport Temperature

Room temperature

Specimen Stability

Room temperature: 7 days
Refrigerated: 14 days
Frozen: 30 days

Reject Criteria

Gross hemolysis

Setup Schedule

Service Area must be determined

Preferred Specimen(s)

1 mL serum

Minimum Volume

0.3 mL

Transport Container

Transport tube

Transport Temperature

Room temperature

Specimen Stability

Room temperature: 7 days
Refrigerated: 14 days
Frozen: 30 days

Reject Criteria

Gross hemolysis

Setup Schedule

Service Area must be determined

Not offered in Quest Diagnostics Nichols Institute (IFD) – San Juan Capistrano. Please provide SERVICE AREA INFORMATION to find available tests you can order.

In-home collection may be available in your area for purchase through Quest Mobile.

Test Details

Clinical Significance

Test Resources

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

The CPT codes provided are based on AMA guidance and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

This material contains content from LOINC® (http://loinc.org). The LOINC Table, LOINC Table Core are copyright © 1995-2019, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license.

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