Direct Antiglobulin Test (DAT) with Reflex to Anti C3 and Anti IgG

Test Code

36668

CPT Code(s)

86880

Test Code

36668

CPT Code(s)

86880

Not offered in Quest Nichols Institute - Chantilly, VA | Quest Diagnostics Nichols Institute (IFD) – San Juan Capistrano. Please provide SERVICE AREA INFORMATION to find available tests you can order.

In-home collection may be available in your area for purchase through Quest Mobile.

Clinical Significance

Direct Antiglobulin Test (DAT) with Reflex to Anti C3 and Anti IgG - The DAT (Direct Coomb's test) is positive if red cells have been coated, in vivo, with immunoglobulin, complement, or both. A positive result can occur in immune-mediated red cell destruction, autoimmune hemolytic anemia, a transfusion reaction or in patients receiving certain drugs.

Test Resources

None found for this test
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Test Details

Includes

If Direct Antiglobulin is positive, then Anti C3 and Anti IgG will be performed at an additional charge (CPT code(s): 86880 x2).

Methodology

Agglutination

Reference Range(s)

Negative

Alternative Name(s)

Direct Coombs,Coombs Direct

LOINC® Codes, Performing Laboratory

Service Area must be determined

Includes

If Direct Antiglobulin is positive, then Anti C3 and Anti IgG will be performed at an additional charge (CPT code(s): 86880 x2).

Methodology

Agglutination

Reference Range(s)

Negative

Alternative Name(s)

Direct Coombs,Coombs Direct

LOINC® Codes, Performing Laboratory

Service Area must be determined

Preferred Specimen(s)

5 mL whole blood collected in an EDTA (pink-top) tube

Alternative Specimen(s)

Whole blood collected in: ACD (yellow-top) tube, EDTA (lavender-top) tube or Cord blood collected in a red top tube (no gel)

Minimum Volume

5 mL

Collection Instructions

If submitting with a CBC, HbA1c, or any other test requiring an EDTA (lavender-top) tube, please submit a separate tube for this test

Transport Container

EDTA (pink-top) tube

Transport Temperature

Refrigerated (cold packs)

Specimen Stability

Room temperature: 24 hours
Refrigerated: 72 hours
Frozen: Unacceptable

Reject Criteria

Gross hemolysis • Grossly lipemic • Serum separator tube (SST) • Clotted specimen• Grossly icteric

Setup Schedule

Service Area must be determined

Preferred Specimen(s)

5 mL whole blood collected in an EDTA (pink-top) tube

Alternative Specimen(s)

Whole blood collected in: ACD (yellow-top) tube, EDTA (lavender-top) tube or Cord blood collected in a red top tube (no gel)

Minimum Volume

5 mL

Collection Instructions

If submitting with a CBC, HbA1c, or any other test requiring an EDTA (lavender-top) tube, please submit a separate tube for this test

Transport Container

EDTA (pink-top) tube

Transport Temperature

Refrigerated (cold packs)

Specimen Stability

Room temperature: 24 hours
Refrigerated: 72 hours
Frozen: Unacceptable

Reject Criteria

Gross hemolysis • Grossly lipemic • Serum separator tube (SST) • Clotted specimen• Grossly icteric

Setup Schedule

Service Area must be determined

In-home collection may be available in your area for purchase through Quest Mobile.

Test Details

Clinical Significance

Test Resources

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

The CPT codes provided are based on AMA guidance and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

This material contains content from LOINC® (http://loinc.org). The LOINC Table, LOINC Table Core are copyright © 1995-2019, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license.

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