Cryoglobulin (% Cryocrit), Serum
Test code
CPT code(s)*
Test resources
Clinical focus
Details
Methodology
Visual Inspection
Alternative name(s)
CRYOS
Specimen requirements | |
|---|---|
| Patient preparation | Overnight fasting is required |
| Preferred specimen(s) | 3 mL serum collected in a red-top tube (no gel) |
| Minimum volume | 2 mL |
| Collection instructions | Allow blood to clot for one (1) hour in a 37° C water bath, incubator, heat block or heel warmer. After clotting, centrifuge the specimen as quickly as possible. It is not necessary to use a warm centrifuge but do not use a refrigerated one. Decant all of the serum into one transport vial (do not aliquot any of the cryoglobulin serum into any other tube). Transport at room temperature preferred. Note: If the sample is not kept at 37° C during clotting, the cryoglobulin, if present, can precipitate during centrifugation and be lost in the clot resulting in a false negative result. |
| Transport container | Transport tube |
| Transport temperature | Room temperature |
| Specimen stability | Room temperature: 14 days Refrigerated: 14 days Frozen: 30 days |
| Reject criteria | Gross hemolysis • Grossly lipemic • Serum separator tube (SST) • Icteric sample |
Reference Range(s)
| Cryoglobulin Qualitative | Negative |
| % Cryocrit | None detected |
Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.
*The CPT codes provided are based on AMA guidance and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.
This material contains content from LOINC® (http://loinc.org). The LOINC Table, LOINC Table Core are copyright © 1995-2019, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license.
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