Cardio IQ® Insulin Resistance Panel with Score

Test code

36509

CPT code(s)*

83525, 84681

Not offered in Quest Diagnostics Nichols Institute (IFD) – San Juan Capistrano. Please provide Service Area Information to find available tests you can order.

In-home collection may be available in your area for purchase through Quest Mobile.

Clinical significance

Cardio IQ® Insulin Resistance Panel with Score - The determination of insulin in serum is primarily used for the diagnosis of glycemic disorders in diabetic and pre-diabetic patients in the assessment of insulin resistant syndromes. Insulin is synthesized by the pancreatic beta cell as a precursor, proinsulin. Proinsulin is processed to insulin and C-peptide, a contiguous peptide between the insulin A and B chains, as it passes through the cell. The C-peptide in the proinsulin ensures correct folding and processing of proinsulin as it passes through the cell. Both insulin and C-peptide are released together from the beta cells in response to increased glucose levels. Because…

Test resources

Details

Test details

Includes

Insulin, Intact, LC/MS/MS
C-Peptide, LC/MS/MS
Insulin Resistance Score

Methodology

Immunocapture Liquid Chromatography/Tandem Mass Spectrometry

Assay category

This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Alternative name(s)

CardioIQ®,IR Score,IR Risk Score,IRR Score,IRS,CIQ Insulin,CIQ IRS

Specimen requirements
Patient preparation	Overnight fasting is required
Preferred specimen(s)	0.5 mL serum
Minimum volume	0.4 mL
Collection instructions	Allow serum samples to clot completely before centrifugation
Transport container	Transport tube
Transport temperature	Refrigerated (cold packs)
Specimen stability	Room temperature: 24 hours Refrigerated: 7 days Frozen: 28 days
Reject criteria	Hemolysis

Reference range(s)

Reference Range(s)

Insulin, Intact, LC/MS/MS	≤16 uIU/mL
C-peptide, LC/MS/MS	0.68-2.16 ng/mL
Insulin Resistance Score	≤66

LOINC® codes

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Service Area Information

Performing lab & setup schedule

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Service Area Information

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

*The CPT codes provided are based on AMA guidance and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

This material contains content from LOINC® (http://loinc.org). The LOINC Table, LOINC Table Core are copyright © 1995-2019, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license.

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