Copper, 24-Hour Urine
Test Code
365
82525
CPT Code is subject to a Medicare Limited Coverage Policy and may require a signed ABN when ordering.
In-home collection is not available in your area through Quest Mobile.
Clinical Significance
Copper, 24-Hour Urine - Copper is an essential element that is a cofactor of many enzymes. Copper metabolism is disturbed in Wilson's disease, Menkes disease, primary biliary cirrhosis, and Indian childhood cirrhosis. Urinary copper concentrations are also useful to monitor patients on chealation therapy.
Test Resources
None found for this test
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Please visit our Clinical Education Center to stay informed on any future publications, webinars, or other education opportunities.
Test Details
CPT code 81050 may be added at an additional charge for volume measurement
Methodology
Inductively Coupled Plasma/Mass Spectrometry (ICP/MS)
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Reference Range(s)
15-60 mcg/24 h
Preferred Specimen(s)
7 mL aliquot of a well-mixed 24-hour urine collected in an acid-washed or metal-free container
Minimum Volume
3 mL
Collection Instructions
Collect without preservative and transport in an acid-washed or metal-free plastic container. Record total volume on specimen container and on test requisition. To avoid contamination, do not measure 24-hour volume.
Transport Container
Acid-washed plastic urine container
Transport Temperature
Room temperature
Specimen Stability
- Room temperature: 5 days
- Refrigerated: 14 days
- Frozen: 30 days
Reject Criteria
Hemolysis • Random urine • Fecal contamination
Setup Schedule
7 mL aliquot of a well-mixed 24-hour urine collected in an acid-washed or metal-free container
3 mL
Collect without preservative and transport in an acid-washed or metal-free plastic container. Record total volume on specimen container and on test requisition. To avoid contamination, do not measure 24-hour volume.
Acid-washed plastic urine container
Room temperature
Room temperature: 5 days
Refrigerated: 14 days
Frozen: 30 days
Refrigerated: 14 days
Frozen: 30 days
Hemolysis • Random urine • Fecal contamination