Herpes Simplex Virus 1 (IgG), Type-Specific Antibody

Herpes Simplex Virus 1 (IgG), Type-Specific Antibody

Test Code

3636
86695
3636
86695
In-home collection may be available in your area for purchase through Quest Mobile.

Clinical Significance

Herpes Simplex Virus 1 (IgG), Type-Specific Antibody -

Herpes Simplex Virus (HSV) is responsible for several clinically significant human viral diseases, with severity ranging from inapparent to fatal. Clinical manifestations include genital tract infections, neonatal herpes, meningoencephalitis, keratoconjunctivitis, and gingivostomatitis. There are two HSV serotypes that are closely related antigenically. HSV type 2 is more commonly associated with genital tract and neonatal infections, while HSV type 1 is more commonly associated with infections of non-genital sites. Specific typing is not usually required for diagnosis or treatment. The mean ...

Test Resources

Test FAQ

Herpes Simplex Virus (HSV) Type-Specific IgG Antibodies

Test Details

Methodology

Immunoassay (IA)

Reference Range(s)

Index Interpretation
<0.90 Negative
0.90-1.09 Equivocal
>1.09 Positive
This assay utilizes recombinant type-specific antigens to differentiate HSV-1 from HSV-2 infections. A index positive result cannot distinguish between recent and past infection. If recent HSV infection is suspected but the results are negative or equivocal, the assay should be repeated in 4-6 weeks. The performance index characteristics of the assay have not been established for pediatric populations, immunocompromised patients, or neonatal screening.

LOINC® Codes, Performing Laboratory

Service Area must be determined

Methodology

Immunoassay (IA)

Reference Range(s)

Index Interpretation
<0.90 Negative
0.90-1.09 Equivocal
>1.09 Positive
This assay utilizes recombinant type-specific antigens to differentiate HSV-1 from HSV-2 infections. A index positive result cannot distinguish between recent and past infection. If recent HSV infection is suspected but the results are negative or equivocal, the assay should be repeated in 4-6 weeks. The performance index characteristics of the assay have not been established for pediatric populations, immunocompromised patients, or neonatal screening.
Service Area must be determined

Preferred Specimen(s)

1 mL serum

Minimum Volume

0.5 mL

Transport Container

Transport tube

Transport Temperature

Room temperature

Specimen Stability

  • Room temperature: 7 days
  • Refrigerated: 14 days
  • Frozen: 30 days
  •  

Reject Criteria

Gross hemolysis • Grossly lipemic • Plasma

Setup Schedule

Service Area must be determined
1 mL serum
0.5 mL
Transport tube
Room temperature
Room temperature: 7 days
Refrigerated: 14 days
Frozen: 30 days
Gross hemolysis • Grossly lipemic • Plasma
Service Area must be determined
In-home collection may be available in your area for purchase through Quest Mobile.
Test Details

Clinical Significance

Test Resources

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

The CPT codes provided are based on AMA guidance and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

This material contains content from LOINC® (http://loinc.org). The LOINC Table, LOINC Table Core are copyright © 1995-2019, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license.

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