Dihydrotestosterone, Free, Serum

Test Code

36168

CPT Code(s)

82642

Test Code

36168

CPT Code(s)

82642

Not offered in Quest Diagnostics Nichols Institute (IFD) – San Juan Capistrano. Please provide SERVICE AREA INFORMATION to find available tests you can order.

In-home collection may be available in your area for purchase through Quest Mobile.

Clinical Significance

Dihydrotestosterone, Free, Serum - This test measures serum concentration of dihydrotestosterone (DHT) and may help diagnose 5-alpha-reductase deficiency, an autosomal recessive condition that affects male sexual development [1]. Measurement of DHT levels has also been used to evaluate therapies affecting androgens levels.

DHT is the most potent androgen and plays an important role in male external genitalia development, prostate growth, and skin metabolism. DHT is largely derived from testosterone via 5-alpha-reductase activity in the peripheral tissues but can also be synthesized through a "backdoor pathway" without testosterone ...

Test Resources

None found for this test
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Test Details

Includes

Dihydrotestosterone and DHT, Free

Methodology

Equilibrium Dialysis • Chromatography/Mass Spectrometry

Assay Category

This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Reference Range(s)

Dihydrotestosterone
Females	≤20 ng/dL
Males	12-65 ng/dL
DHT, Free
Adult female	≤0.91 pg/mL
Adult male	0.62-3.38 pg/mL

LOINC® Codes, Performing Laboratory

Service Area must be determined

Includes

Dihydrotestosterone and DHT, Free

Methodology

Equilibrium Dialysis • Chromatography/Mass Spectrometry

Assay Category

Reference Range(s)

Dihydrotestosterone
Females	≤20 ng/dL
Males	12-65 ng/dL
DHT, Free
Adult female	≤0.91 pg/mL
Adult male	0.62-3.38 pg/mL

LOINC® Codes, Performing Laboratory

Service Area must be determined

Preferred Specimen(s)

1.5 mL serum collected in a red-top tube (no gel)

Minimum Volume

1 mL

Transport Container

Transport tube

Transport Temperature

Refrigerated (cold packs)

Specimen Stability

Room temperature: 72 hours
Refrigerated: 14 days
Frozen: 6 months

Reject Criteria

Moderate to gross hemolysis • Grossly icteric • Serum separator tube (SST) • Plasma

Setup Schedule

Service Area must be determined

Preferred Specimen(s)

1.5 mL serum collected in a red-top tube (no gel)

Minimum Volume

1 mL

Transport Container

Transport tube

Transport Temperature

Refrigerated (cold packs)

Specimen Stability

Room temperature: 72 hours
Refrigerated: 14 days
Frozen: 6 months

Reject Criteria

Moderate to gross hemolysis • Grossly icteric • Serum separator tube (SST) • Plasma

Setup Schedule

Service Area must be determined

Not offered in Quest Diagnostics Nichols Institute (IFD) – San Juan Capistrano. Please provide SERVICE AREA INFORMATION to find available tests you can order.

In-home collection may be available in your area for purchase through Quest Mobile.

Test Details

Clinical Significance

Test Resources

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

The CPT codes provided are based on AMA guidance and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

This material contains content from LOINC® (http://loinc.org). The LOINC Table, LOINC Table Core are copyright © 1995-2019, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license.

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