Hemoglobinopathy Evaluation

Test Code

35489

CPT Code(s)

83020, 85014, 85018, 85041

CPT Code is subject to a Medicare Limited Coverage Policy and may require a signed ABN when ordering.

Test Code

35489

CPT Code(s)

83020, 85014, 85018, 85041

CPT Code is subject to a Medicare Limited Coverage Policy and may require a signed ABN when ordering.

Not offered in Quest Diagnostics Nichols Institute (IFD) – San Juan Capistrano. Please provide SERVICE AREA INFORMATION to find available tests you can order.

In-home collection may be available in your area for purchase through Quest Mobile.

Clinical Significance

Hemoglobinopathy Evaluation - The detection and proper identification of hemoglobinopathies and thalassemias is an important aspect of the evaluation of patients with anemia, microcytosis and erythrocytosis.

Test Resources

None found for this test
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Test Details

Includes

Hemoglobin A, Hemoglobin F, Hemoglobin A2 (Quant), Hemoglobin S, Hemoglobin C, Hemoglobin E, and any hemoglobin variants
Red Blood Cell Count, Hemoglobin, Hematocrit, MCV, MCH, RDW

Methodology

Electronic Sizing and Counting/Cytometry • Capillary Electrophoresis followed by, if necessary, High Performance Liquid Chromatography (HPLC)

Reference Range(s)

See Laboratory Report

Alternative Name(s)

HGB Evaluation,Hemoglobin A2,Hemoglobin Variants,HGB Variants,Hemoglobin Electrophoresis,HGB Electrophoresis,Hemoglobin S,Thalassemia Screen,HB A2,HB F,HB S,Hemoglobin F

LOINC® Codes, Performing Laboratory

Service Area must be determined

Includes

Hemoglobin A, Hemoglobin F, Hemoglobin A2 (Quant), Hemoglobin S, Hemoglobin C, Hemoglobin E, and any hemoglobin variants
Red Blood Cell Count, Hemoglobin, Hematocrit, MCV, MCH, RDW

Methodology

Electronic Sizing and Counting/Cytometry • Capillary Electrophoresis followed by, if necessary, High Performance Liquid Chromatography (HPLC)

Reference Range(s)

See Laboratory Report

Alternative Name(s)

HGB Evaluation,Hemoglobin A2,Hemoglobin Variants,HGB Variants,Hemoglobin Electrophoresis,HGB Electrophoresis,Hemoglobin S,Thalassemia Screen,HB A2,HB F,HB S,Hemoglobin F

LOINC® Codes, Performing Laboratory

Service Area must be determined

Preferred Specimen(s)

1 full (5 mL) EDTA (lavender-top) tube

Alternative Specimen(s)

Whole blood collected in an EDTA (tan-top), (pink-top) or (royal blue-top) tube

Minimum Volume

1 mL

Collection Instructions

Patient age and ethnicity are necessary for proper interpretation.
Blood transfusions within the last 4 months may affect results.

Note: If tube drawn is shared with lead testing, trace metal-free EDTA (i.e. royal blue-top or tan-top) tube is required.

Transport Container

EDTA (lavender-top) tube

Specimen Stability

Room temperature: 72 hours
Refrigerated: 7 days
Frozen: Unacceptable

Reject Criteria

Gross hemolysis • Clotted

Setup Schedule, Transport Temperature

Service Area must be determined

Preferred Specimen(s)

1 full (5 mL) EDTA (lavender-top) tube

Alternative Specimen(s)

Whole blood collected in an EDTA (tan-top), (pink-top) or (royal blue-top) tube

Minimum Volume

1 mL

Collection Instructions

Transport Container

EDTA (lavender-top) tube

Specimen Stability

Room temperature: 72 hours
Refrigerated: 7 days
Frozen: Unacceptable

Reject Criteria

Gross hemolysis • Clotted

Setup Schedule, Transport Temperature

Service Area must be determined

Not offered in Quest Diagnostics Nichols Institute (IFD) – San Juan Capistrano. Please provide SERVICE AREA INFORMATION to find available tests you can order.

In-home collection may be available in your area for purchase through Quest Mobile.

Test Details

Clinical Significance

Test Resources

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

The CPT codes provided are based on AMA guidance and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

This material contains content from LOINC® (http://loinc.org). The LOINC Table, LOINC Table Core are copyright © 1995-2019, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license.

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