HIV-1 Genotype

Test code

34949

CPT code(s)*

87900, 87901

In-home collection may be available in your area for purchase through Quest Mobile.

Clinical significance

HIV-1 Genotype - This test is intended for use in conjunction with clinical presentation and other laboratory markers of disease progress for the clinical management of HIV-1 infected patients. The test identifies drug resistance-associated mutations in the HIV-1 protease and reverse transcriptase genes. It can be used to predict antiretroviral drug resistance before initiation of therapy and in patients experiencing virologic failure while on therapy.

Test resources

Details

Test details

Methodology

DNA Sequencing • Reverse Transcriptase Polymerase Chain Reaction (RT-PCR)

Assay category

This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Specimen requirements
Patient preparation	None Specified
Preferred specimen(s)	2 mL plasma collected in an EDTA (lavender-top) tube or PPT (white-top) tube
Alternative specimen(s)	2 mL CSF collected in a sterile leak-proof container
Minimum volume	0.6 mL plasma • 0.6 mL CSF
Collection instructions	Do not freeze whole blood or any samples stored in primary tube. Freshly drawn specimens (whole blood) may be stored at 2-25° C for up to 24 hours prior to centrifugation. Separate plasma from cells within 24 hours of collection by centrifugation. If shipping frozen, transfer plasma to a leak-proof transport tube, then freeze prior to shipment. Follow manufacturer's instructions for collection tube handling. CSF: Collect CSF using standard procedures. Transfer to a sterile, leak-proof container. Ship frozen.
Transport container	Transport tube
Transport temperature	Frozen
Specimen stability	Room temperature: 24 hours Refrigerated: 6 days Frozen: 42 days
Reject criteria	Plasma received frozen in the plasma preparation tube (PPT) • Serum • Whole blood >24 hours old • Frozen whole blood

Reference range(s)

See Laboratory Report

LOINC® codes

The Result and LOINC® information listed below should not be used for electronic interface maintenance with Quest Diagnostics. Please contact the Quest Diagnostics Connectivity Help Desk for more information at 800-697-9302.

NOTE: The codes listed in the table are not orderable Test Codes

Result code	Result name	LOINC code	Component name
86007864	HIV 1 GENOTYPE	48558-1	HIV genotype

Performing lab & setup schedule

Performing laboratory

Quest Diagnostics Nichols Institute-San Juan Capistrano, CA

33608 Ortega Highway

San Juan Capistrano, CA 92675-2042

Setup schedule

Set up: Mon-Sat; Report available: 12 days

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

*The CPT codes provided are based on AMA guidance and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

This material contains content from LOINC® (http://loinc.org). The LOINC Table, LOINC Table Core are copyright © 1995-2019, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license.

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