Glutamic Acid Decarboxylase-65 Antibody

Glutamic Acid Decarboxylase-65 Antibody

Test Code

34878
86341
34878
86341
In-home collection may be available in your area for purchase through Quest Mobile.

Clinical Significance

Glutamic Acid Decarboxylase-65 Antibody - Key clinical use and differentiators
Measurement of Glutamic acid decarboxylase (GAD65) is used to: 1. Screen for presymptomatic type 1 diabetes (T1D) in individuals with a family history of T1D or those known to have a high-risk HLA genotype, 2. Distinguish between T1D, type 2 diabetes mellitus (T2D), and atypical forms of diabetes such as latent autoimmune diabetes in adults (LADA). [1] Glutamic acid decarboxylase (GAD65) is a key protein that the immune system mistakenly attacks in people with T1D, and positivity to GAD65 antibodies represents a key marker of the disease. [1] GAD65 is the ...

Test Resources

Test FAQ

Autoantibodies and Type 1 Diabetes (T1D)

Algorithm

Staging presymptomatic patients using Diabetes Type 1 Autoantibody Panel

Test Summary

Diabetes Type 1 Autoantibody Panel

Test Details

Methodology

Enzyme Linked Immunosorbent Assay (ELISA)

Reference Range(s)

<5 IU/mL

LOINC® Codes, Performing Laboratory

Service Area must be determined

Methodology

Enzyme Linked Immunosorbent Assay (ELISA)

Reference Range(s)

<5 IU/mL

Service Area must be determined

Preferred Specimen(s)

1 mL serum

Minimum Volume

0.5 mL

Transport Container

Transport tube

Transport Temperature

Room temperature

Specimen Stability

  • Room temperature: 7 days
  • Refrigerated: 14 days
  • Frozen: 60 days

Setup Schedule

Service Area must be determined
1 mL serum
0.5 mL
Transport tube
Room temperature
Room temperature: 7 days
Refrigerated: 14 days
Frozen: 60 days
Service Area must be determined
In-home collection may be available in your area for purchase through Quest Mobile.
Test Details

Clinical Significance

Test Resources

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

The CPT codes provided are based on AMA guidance and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

This material contains content from LOINC® (http://loinc.org). The LOINC Table, LOINC Table Core are copyright © 1995-2019, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license.

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