Tryptase | Test Detail | Quest Diagnostics

Tryptase

Test Code

34484

CPT Code(s)

83520

Test Code

34484

CPT Code(s)

83520

Not offered in Quest Diagnostics Nichols Institute (IFD) – San Juan Capistrano. Please provide SERVICE AREA INFORMATION to find available tests you can order.

In-home collection is not available in your area through Quest Mobile.

Clinical Significance

Tryptase - This test may be used as a marker of mast cell activity. Tryptase is a serine protease released by mast cells constitutively (alpha-tryptase) and during activation (beta-tryptase). Serum measurement detects both forms and does not differentiate them [1]. Elevated basal tryptase levels are not uncommon and in most cases are due to hereditary alpha tryptasemia [2]. They are also seen in mastocytosis, other myeloid disorders, allergic disorders, chronic renal failure and some chronic infections [3]. Using tryptase to confirm anaphylaxis may require drawing the sample within 30 minutes - 6 hours of ...

Test Resources

None found for this test
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Test Details

Methodology

Immunoassay (IA)

Reference Range(s)

<11.0 mcg/L

LOINC® Codes, Performing Laboratory

Service Area must be determined

Methodology

Immunoassay (IA)

Reference Range(s)

<11.0 mcg/L

LOINC® Codes, Performing Laboratory

Service Area must be determined

Preferred Specimen(s)

1 mL serum

Minimum Volume

0.5 mL

Collection Instructions

Samples should be obtained between 15 minutes and 3 hours after the event suspected of causing mast cell activation. When sample is drawn, separate serum from cells within 3 hours of collection.

Transport Container

Transport tube

Transport Temperature

Refrigerated (cold-packs)

Specimen Stability

Room temperature: Unacceptable
Refrigerated: 7 days
Frozen: 30 days

Setup Schedule

Service Area must be determined

Preferred Specimen(s)

1 mL serum

Minimum Volume

0.5 mL

Collection Instructions

Samples should be obtained between 15 minutes and 3 hours after the event suspected of causing mast cell activation. When sample is drawn, separate serum from cells within 3 hours of collection.

Transport Container

Transport tube

Transport Temperature

Refrigerated (cold-packs)

Specimen Stability

Room temperature: Unacceptable
Refrigerated: 7 days
Frozen: 30 days

Setup Schedule

Service Area must be determined

Not offered in Quest Diagnostics Nichols Institute (IFD) – San Juan Capistrano. Please provide SERVICE AREA INFORMATION to find available tests you can order.

In-home collection is not available in your area through Quest Mobile.

Test Details

Clinical Significance

Test Resources

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

The CPT codes provided are based on AMA guidance and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

This material contains content from LOINC® (http://loinc.org). The LOINC Table, LOINC Table Core are copyright © 1995-2019, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license.

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