Filaria Antibody (IgG4)

Test Code

34168

CPT Code(s)

86682

Test Code

34168

CPT Code(s)

86682

Ordering Restrictions may apply. Please provide SERVICE AREA INFORMATION to find available tests you can order.

In-home collection may be available in your area for purchase through Quest Mobile.

Clinical Significance

Filaria Antibody (IgG4) -

The filaria IgG4 assay may be helpful in the diagnosis of infections with major filaria parasites, including Wuchereria brancrofti, Brugia malayi, Onchocerca volvulus, and Dirofilaria immitis. Because cross-reactivity may occur in infections with other nematodes, identification of parasites in blood or other body fluid remains the definitive means of diagnosis [2]. A negative result on this test does not rule out chronic filarial infection.

W bancrofti and B malayi cause lymphatic filariasis, a disease transmitted by mosquitoes and characterized by swollen lymph ...

Test Resources

None found for this test
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Test Details

Methodology

Immunoassay (IA)

Assay Category

This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Reference Range(s)

<2.50 index

Interpretive Criteria

<2.50	Negative
≥2.50	Positive

This assay detects Filaria IgG4 associated with index infections caused by the major filarial parasites, including Dirofilaria immitis, Wuchereria brancrofti, Brugia malayi, and Onchocerca volvulus. Chronic filarial infections manifesting as elephantiasis may not show a significant IgG4 response and cannot be index ruled out using this test. Samples containing antibodies to other nematodes, particularly Strongyloides, may cross-react in the assay.

Alternative Name(s)

Filariasis

LOINC® Codes, Performing Laboratory

Service Area must be determined

Methodology

Immunoassay (IA)

Assay Category

Reference Range(s)

<2.50 index

Interpretive Criteria

<2.50	Negative
≥2.50	Positive

Alternative Name(s)

Filariasis

LOINC® Codes, Performing Laboratory

Service Area must be determined

Preferred Specimen(s)

0.2 mL serum

Minimum Volume

0.1 mL

Transport Container

Transport tube

Transport Temperature

Room temperature

Specimen Stability

Room temperature: 7 days
Refrigerated: 14 days
Frozen: 30 days

Reject Criteria

CSF

Setup Schedule

Service Area must be determined

Preferred Specimen(s)

0.2 mL serum

Minimum Volume

0.1 mL

Transport Container

Transport tube

Transport Temperature

Room temperature

Specimen Stability

Room temperature: 7 days
Refrigerated: 14 days
Frozen: 30 days

Reject Criteria

CSF

Setup Schedule

Service Area must be determined

Ordering Restrictions may apply. Please provide SERVICE AREA INFORMATION to find available tests you can order.

In-home collection may be available in your area for purchase through Quest Mobile.

Test Details

Clinical Significance

Test Resources

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

The CPT codes provided are based on AMA guidance and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

This material contains content from LOINC® (http://loinc.org). The LOINC Table, LOINC Table Core are copyright © 1995-2019, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license.

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