Measles Antibodies (IgG, IgM), Diagnostic
Test Code
34166
86765 (x2)
Clinical Significance
Measles Antibodies (IgG, IgM), Diagnostic - Measles, also known as Rubeola, causes fever, irritability, respiratory illness, and the characteristic skin rash. Immunization has greatly diminished the incidence of measles. The presence of IgG is consistent with immunity or prior exposure. IgM is consistent with current or recent infection. IgM tests can generate false positive results and low levels of IgM can persist for longer than 12 months.
Test Resources
Test FAQ
Measles (Rubeola)Test Details
Methodology
Immunoassay (IA) • Immunofluorescence Assay (IFA)
Measles Antibodies (IgM): This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Reference Range(s)
Measles Antibody (IgG)
The presence of measles IgG suggests immunization or past or current infection with measles virus.
Measles Antibody (IgM)
The traditional serologic diagnosis of measles requires a significant rise in antibody titer between acute and convalescent sera. However, detection of IgM antibody in a single specimen may indicate acute disease.
Correct interpretation of serologic data depends upon the proper timing of specimen collection in relation to rash onset. This timing is particularly important for interpreting negative IgM results, since IgM antibody peaks approximately 10 days after rash onset and is usually undetectable 30 days after rash onset.
| AU/mL | Interpretation |
| <13.50 | Negative |
| 13.50-16.49 | Equivocal |
| >16.49 | Positive |
Measles Antibody (IgM)
| Titer | Interpretation |
| <1:20 | Antibody not detected |
| ≥1:20 | Antibody detected |
Correct interpretation of serologic data depends upon the proper timing of specimen collection in relation to rash onset. This timing is particularly important for interpreting negative IgM results, since IgM antibody peaks approximately 10 days after rash onset and is usually undetectable 30 days after rash onset.
Alternative Name(s)
Rubeola IgG and IgM Antibodies
Preferred Specimen(s)
1 mL serum
Minimum Volume
0.5 mL
Transport Container
Transport tube
Transport Temperature
Room temperature
Specimen Stability
- Room temperature: 4 days
- Refrigerated: 7 days
- Frozen: 30 days
Setup Schedule
1 mL serum
0.5 mL
Transport tube
Room temperature
Room temperature: 4 days
Refrigerated: 7 days
Frozen: 30 days
Refrigerated: 7 days
Frozen: 30 days