Clonazepam
Test Code
340
80299
CPT Code is subject to a Medicare Limited Coverage Policy and may require a signed ABN when ordering.
Clinical Significance
Clonazepam -
Clonazepam is a benzodiazepine used as a tranquilizer. Clonazepam is used in treating patients with seizures and in reducing tardive dyskinesia. Therapeutic drug monitoring is useful to avoid toxicity.
Test Resources
Test Details
Collect at trough concentration, immediately before the administration of the next dose
Methodology
Chromatography/Mass Spectrometry
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Reference Range(s)
30-60 mcg/L
Alternative Name(s)
Clonopin, Klonopin, Rivotril
Preferred Specimen(s)
2 mL serum collected in a red-top tube (no gel)
Alternative Specimen(s)
Plasma collected in: EDTA (lavender-top) tube, sodium heparin (green-top) tube, or lithium heparin (green-top) tube
Minimum Volume
1 mL
Transport Container
Transport tube
Transport Temperature
Frozen
Specimen Stability
- Room temperature: 24 hours
- Refrigerated: 72 hours
- Frozen: 14 days
Reject Criteria
Serum separator tube (SST)
Setup Schedule
2 mL serum collected in a red-top tube (no gel)
Plasma collected in: EDTA (lavender-top) tube, sodium heparin (green-top) tube, or lithium heparin (green-top) tube
1 mL
Transport tube
Frozen
Room temperature: 24 hours
Refrigerated: 72 hours
Frozen: 14 days
Refrigerated: 72 hours
Frozen: 14 days
Serum separator tube (SST)