Cholinesterase, RBC and Plasma
Test code
CPT code(s)*
Test resources
Please visit our Clinical Education Center to stay informed on any future publications, webinars, or other education opportunities.
Details
Methodology
Kinetic Spectrophotometric (KS)
Assay category
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
This test code is for non-California patient testing. For California patient testing, use test code 90372.
Alternative name(s)
RBC Cholinesterase
Specimen requirements | |
|---|---|
| Patient preparation | None Specified |
| Preferred specimen(s) | 4 mL whole blood collected in an EDTA (lavender-top) and 1 mL plasma collected in an EDTA (lavender-top) |
| Minimum volume | 3 mL whole blood • 0.5 mL plasma |
| Collection instructions | Draw two EDTA (lavender-top) tubes of whole blood. Spin one tube to separate plasma. Pour plasma into plastic aliquot tube (label this vial as plasma). Send one 4 mL refrigerated uncentrifuged whole blood (3 mL minimum) and 1 mL refrigerated plasma (0.5 mL minimum). Do not send packed cells. Do not send only one tube of whole blood. Plasma cholinesterase results, as well as the calculated RBC cholinesterase results, are not accurate if plasma sample is not separated from the RBC's in a timely manner. Hemolyzed plasma samples are not acceptable. Hemolysis can lead to apparent increases in plasma cholinesterase activity, and could mask an enzyme deficiency. |
| Transport container | EDTA (lavender-top) tube and transport tube |
| Transport temperature | Refrigerated (cold packs) |
| Specimen stability | Room temperature: 24 hours Refrigerated: 7 days Frozen: Unacceptable |
| Reject criteria | Hemolysis • Lipemia • Received room temperature • Receipt of only a single tube of whole blood |
Reference Range(s)
| Cholinesterase, RBC | 9572-15031 IU/L |
| Cholinesterase, Plasma | |
| Male | 3334-7031 IU/L |
| Female | 2504-6297 IU/L |
Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.
*The CPT codes provided are based on AMA guidance and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.
This material contains content from LOINC® (http://loinc.org). The LOINC Table, LOINC Table Core are copyright © 1995-2019, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license.
The tests listed by specialty and category are a select group of tests offered. For a complete list of Quest Diagnostics tests, please adjust the filter options chosen, or refer to our Directory of Services.