Carboxyhemoglobin, Blood
Test Code
Clinical Significance
Carboxyhemoglobin, Blood - Carbon monoxide is the most common of the gaseous poisons. Malfunctioning or poorly ventilated heating appliances and internal combustion engines are frequent causes of carbon monoxide poisoning. Carbon monoxide combines reversibly with hemoglobin in a manner almost identical to oxygen resulting in a decrease in the amount of oxygen carried by hemoglobin. Accidental poisoning can occur even at low levels (greater than 0.01%) of CO in the atmosphere with prolonged exposure.
Test Resources
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Test Details
Methodology
Reference Range(s)
| Non-Smoker | <2 % of total Hgb |
| Average Smoker | 4-5 % of total Hgb |
| Heavy Smoker | 8-12 % of total Hgb |
| Potentially Toxic | >15 % of total Hgb |
Preferred Specimen(s)
Whole blood collected in 1 full EDTA (lavender-top) tube
Alternative Specimen(s)
Whole blood collected in: Sodium heparin (green-top) tube or lithium heparin (green-top) tube
Minimum Volume
0.5 mL
Collection Instructions
Keep tube closed
Transport Container
EDTA (lavender-top) tube
Transport Temperature
Room temperature
Specimen Stability
- Room temperature: 5 days
- Refrigerated: 10 days
- Frozen: Unacceptable
Reject Criteria
Fluoride oxalate (gray-top) tube • Grossly clotted
Setup Schedule
Refrigerated: 10 days
Frozen: Unacceptable