Sex Hormone Binding Globulin (SHBG)
Test Code
Clinical Significance
Sex Hormone Binding Globulin (SHBG) - Testosterone, dihydrotestosterone and estrogens circulate in serum bound to Sex Hormone Binding Globulin (SHBG). SHBG concentrations are increased in pregnancy, hyperthyroidism, cirrhosis, oral estrogen administration and by certain drugs. Concentrations are decreased by testosterone, hypothyroidism, Cushings syndrome, acromegaly and obesity.
Test Details
Methodology
Reference Range(s)
| Male (nmol/L) | Female (nmol/L) | |
| <3 Years | Not Established | Not Established |
| 3-9 Years | 32-158 | 32-158 |
| 10-13 Years | 20-166 | 24-120 |
| 14-17 Years | 20-87 | 12-150 |
| 18-55 Years | 10-50 | 17-124 |
| >55 Years | 22-77 | 14-73 |
Alternative Name(s)
Preferred Specimen(s)
0.7 mL serum
Minimum Volume
0.5 mL
Collection Instructions
Dietary supplements containing biotin may interfere in assays and may skew analyte results to be either falsely high or falsely low. For patients receiving the recommended daily doses of biotin, draw samples at least 8 hours following the last biotin supplementation. For patients on mega-doses of biotin supplements, draw samples at least 72 hours following the last biotin supplementation.
Administration of STRENSIQ may interfere in certain assays and may falsely elevate values. For patients receiving STRENSIQ, consideration should be given to using alternate methods.
Transport Temperature
Room temperature
Specimen Stability
- Room temperature: 7 days
- Refrigerated: 7 days
- Frozen: 28 days
Reject Criteria
Plasma
Setup Schedule, Transport Container
Administration of STRENSIQ may interfere in certain assays and may falsely elevate values. For patients receiving STRENSIQ, consideration should be given to using alternate methods.
Refrigerated: 7 days
Frozen: 28 days