TSI (Thyroid Stimulating Immunoglobulin)
Test Code
30551
84445
In-home collection is not available in your area through Quest Mobile.
Clinical Significance
TSI (Thyroid Stimulating Immunoglobulin) - Graves' disease is a classic form of hyperthyroid disease, affecting approximately 0.4% of the population of the United States. It is caused by IgG immunoglobulins, collectively known as thyroid stimulating immunoglobulins (TSI). Patients who are candidates for antithyroid drug therapy may not respond to this treatment when TSI levels are markedly elevated. The determination of TSI can also assist in predicting hyperthyroidism in neonates, due to placental transmission of the immunoglobulins from a mother with hyperthyroidism.
Test Resources
Clinical Focus
Thyroid Dysfunction in Nonpregnant AdultsTest Details
Methodology
In Vitro Bioassay
Reference Range(s)
<140 % Baseline
Alternative Name(s)
Long Acting Thyroid Stimulator, Thyroid Stimulating Antibody, TSIG, Thyretain™, (LATS)
Preferred Specimen(s)
1 mL serum
Minimum Volume
0.2 mL
Transport Container
Transport tube
Transport Temperature
Refrigerated (cold packs)
Specimen Stability
- Room temperature: Unacceptable
- Refrigerated: 21 days
- Frozen: 60 days
Reject Criteria
Gross hemolysis • Grossly lipemic • Grossly icteric • Plasma
Setup Schedule
1 mL serum
0.2 mL
Transport tube
Refrigerated (cold packs)
Room temperature: Unacceptable
Refrigerated: 21 days
Frozen: 60 days
Refrigerated: 21 days
Frozen: 60 days
Gross hemolysis • Grossly lipemic • Grossly icteric • Plasma