11-Deoxycortisol
Test Code
30543
82634
Clinical Significance
11-Deoxycortisol - 11-Deoxycortisol (Compound S) is useful in diagnosing patients with 11-beta-hydroxylase deficiency (second leading cause of congenital adrenal hyperplasia) and primary (adrenal failure) or secondary (hypothalamic-pituitary ACTH deficiency) adrenal insufficiency.
Test Resources
Clinical Focus
Polycystic Ovary Syndrome (PCOS)Test Details
Methodology
Chromatography/Mass Spectrometry
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Reference Range(s)
See Laboratory Report
Alternative Name(s)
Compound S,Metyrapone Response
Preferred Specimen(s)
1 mL serum
Alternative Specimen(s)
Plasma collected in: EDTA (lavender-top) tube, EDTA (royal blue-top) tube, or sodium heparin (green-top) tube
Minimum Volume
0.5 mL
Collection Instructions
Separate serum after clotting. An early morning specimen is preferred.
Transport Container
Transport tube
Transport Temperature
Refrigerated (cold packs)
Specimen Stability
- Room temperature: 72 hours
Refrigerated: 14 days
Frozen: 1 year
Setup Schedule
1 mL serum
Plasma collected in: EDTA (lavender-top) tube, EDTA (royal blue-top) tube, or sodium heparin (green-top) tube
0.5 mL
Separate serum after clotting. An early morning specimen is preferred.
Transport tube
Refrigerated (cold packs)
Room temperature: 72 hours
Refrigerated: 14 days
Frozen: 1 year
Refrigerated: 14 days
Frozen: 1 year