Estradiol, Ultrasensitive, LC/MS

Estradiol, Ultrasensitive, LC/MS

Test Code

30289
82670
30289
82670
Not offered in Quest Diagnostics Nichols Institute (IFD) – San Juan Capistrano. Please provide SERVICE AREA INFORMATION to find available tests you can order.
In-home collection may be available in your area for purchase through Quest Mobile.

Clinical Significance

Estradiol, Ultrasensitive, LC/MS - Diagnostic applications of estradiol assays include assessment of ovarian function in a wide variety of situations (menstrual disorders, precocious or delayed puberty, assisted reproduction protocols). For men, estradiol measurement may be useful in the evaluation of gynecomastia.

Test Resources

Test FAQ

Hypogonadism

Clinical Focus

Hypogonadism and Low Testosterone in Men: Laboratory Support of Diagnosis and Management

Clinical Focus

Polycystic Ovary Syndrome (PCOS)

Test Details

Methodology

Chromatography/Mass Spectrometry

Assay Category

This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Reference Range(s)

Adult Reference Ranges for Estradiol, Ultrasensitive

Males≤29 pg/mL
Females 
  Follicular Phase39-375 pg/mL
  Luteal Phase48-440 pg/mL
  Postmenopausal Phase≤10 pg/mL

Pediatric Reference Ranges for Estradiol, Ultrasensitive
AgeMales
(pg/mL)		Females
(pg/mL)
Pre-pubertal
  <1 yearNot EstablishedNot Established
  1-9 years≤4≤16
  
10-11 years≤12≤65
12-14 years≤24≤142
15-17 years≤31≤283

LOINC® Codes, Performing Laboratory

Service Area must be determined

Methodology

Chromatography/Mass Spectrometry
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Reference Range(s)

Adult Reference Ranges for Estradiol, Ultrasensitive
Males≤29 pg/mL
Females 
  Follicular Phase39-375 pg/mL
  Luteal Phase48-440 pg/mL
  Postmenopausal Phase≤10 pg/mL

Pediatric Reference Ranges for Estradiol, Ultrasensitive
AgeMales
(pg/mL)		Females
(pg/mL)
Pre-pubertal
  <1 yearNot EstablishedNot Established
  1-9 years≤4≤16
  
10-11 years≤12≤65
12-14 years≤24≤142
15-17 years≤31≤283
Service Area must be determined

Preferred Specimen(s)

0.5 mL serum collected in a red-top tube (no gel)

Minimum Volume

0.2 mL

Collection Instructions

Specify age and sex on test request form

Transport Container

Transport tube

Transport Temperature

Refrigerated (cold packs)

Specimen Stability

  • Room temperature: 24 hours
  • Refrigerated: 7 days
  • Frozen: 28 days

Reject Criteria

Lipemia • Serum separator tube (SST) • Grossly icteric

Setup Schedule

Service Area must be determined
0.5 mL serum collected in a red-top tube (no gel)
0.2 mL
Specify age and sex on test request form
Transport tube
Refrigerated (cold packs)
Room temperature: 24 hours
Refrigerated: 7 days
Frozen: 28 days
Lipemia • Serum separator tube (SST) • Grossly icteric
Service Area must be determined
Not offered in Quest Diagnostics Nichols Institute (IFD) – San Juan Capistrano. Please provide SERVICE AREA INFORMATION to find available tests you can order.
In-home collection may be available in your area for purchase through Quest Mobile.
Test Details

Clinical Significance

Test Resources

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

The CPT codes provided are based on AMA guidance and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

This material contains content from LOINC® (http://loinc.org). The LOINC Table, LOINC Table Core are copyright © 1995-2019, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license.

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