Serotonin, Serum
Test Code
29851
84260
In-home collection is not available in your area through Quest Mobile.
Clinical Significance
Serotonin, Serum - Serotonin concentrations are greatly increased in patients with carcinoid syndrome. Carcinoid tumors are associated with Multiple Endocrine Neoplasia (MEN) Types I and II. These tumors are associated with flushing, diarrhea, pain, and other symptoms.
Test Resources
None found for this test
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Please visit our Clinical Education Center to stay informed on any future publications, webinars, or other education opportunities.
Test Details
Patient should avoid food high in indoles: avocado, banana, tomato, plum, walnut, pineapple, and eggplant.
Patient should also avoid tobacco, tea, and coffee for 3 days before specimen collection.
Patient should also avoid tobacco, tea, and coffee for 3 days before specimen collection.
Methodology
Liquid Chromatography/Tandem Mass Spectrometry (LC/MS/MS)
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Reference Range(s)
56-244 ng/mL
Alternative Name(s)
Serotonin, 5-Hydroxytryptamine
Preferred Specimen(s)
2 mL serum
Minimum Volume
1 mL
Collection Instructions
Spin and freeze serum below -20° C within 2 hours after collection
Transport Container
Transport tube
Transport Temperature
Frozen
Specimen Stability
- Room temperature: Unacceptable
- Refrigerated: Unacceptable
- Frozen: 42 days
Setup Schedule
2 mL serum
1 mL
Spin and freeze serum below -20° C within 2 hours after collection
Transport tube
Frozen
Room temperature: Unacceptable
Refrigerated: Unacceptable
Frozen: 42 days
Refrigerated: Unacceptable
Frozen: 42 days