Lupus Panel 2 with ANA, IFA with Reflex to Titer and Pattern

Test Code

29839

CPT Code(s)

86038, 86225, 86235 (x5)

Test Code

29839

CPT Code(s)

86038, 86225, 86235 (x5)

Not offered in Quest Diagnostics Nichols Institute (IFD) – San Juan Capistrano. Please provide SERVICE AREA INFORMATION to find available tests you can order.

In-home collection may be available in your area for purchase through Quest Mobile.

Clinical Significance

Lupus Panel 2 with ANA, IFA with Reflex to Titer and Pattern -

This panel supports the evaluation of systemic lupus erythematosus (SLE) and related autoimmune diseases, such as mixed connective tissue disease, systemic sclerosis, and Sjogren syndrome. However, testing for subserologies in the absence of a positive antinuclear antibody (ANA) result and clinically suspected autoimmune disease is generally not recommended [1].

This panel simultaneously tests for ANAs with an immunofluorescence assay (IFA) and 6 specific autoantibodies associated rheumatic and related diseases. The ANA testing has high sensitivity (97%) for SLE but limited specificity ...

Test Resources

Clinical Focus

Autoimmune Rheumatic and Related Diseases

Test Details

Includes

ANA Screen,IFA, with Reflex to Titer and Pattern
DNA (ds) Antibodies
Scleroderma Antibodies (SCL-70)
Sm and Sm/RNP Antibodies
Sjogren's Antibodies (SSA, SSB)
If ANA Screen, IFA is positive, then ANA Titer and Pattern will be performed at an additional charge (CPT code(s): 86039).

Methodology

Immunoassay (IA)

Reference Range(s)

See individual tests

Alternative Name(s)

Systemic Lupus Erythematosus (SLE),FANA,Antinuclear Antibody Screen,Fluorescent ANA,Hep-2,Progressive ANA

LOINC® Codes, Performing Laboratory

Service Area must be determined

Includes

ANA Screen,IFA, with Reflex to Titer and Pattern
DNA (ds) Antibodies
Scleroderma Antibodies (SCL-70)
Sm and Sm/RNP Antibodies
Sjogren's Antibodies (SSA, SSB)

If ANA Screen, IFA is positive, then ANA Titer and Pattern will be performed at an additional charge (CPT code(s): 86039).

Methodology

Immunoassay (IA)

Reference Range(s)

See individual tests

Alternative Name(s)

Systemic Lupus Erythematosus (SLE),FANA,Antinuclear Antibody Screen,Fluorescent ANA,Hep-2,Progressive ANA

LOINC® Codes, Performing Laboratory

Service Area must be determined

Preferred Specimen(s)

5 mL serum

Minimum Volume

2 mL

Transport Container

Transport tube

Transport Temperature

Room temperature

Specimen Stability

Room temperature: 4 days
Refrigerated: 7 days
Frozen: 30 days

Reject Criteria

Gross hemolysis • Grossly lipemic • Grossly icteric

Setup Schedule

Service Area must be determined

Preferred Specimen(s)

5 mL serum

Minimum Volume

2 mL

Transport Container

Transport tube

Transport Temperature

Room temperature

Specimen Stability

Room temperature: 4 days
Refrigerated: 7 days
Frozen: 30 days

Reject Criteria

Gross hemolysis • Grossly lipemic • Grossly icteric

Setup Schedule

Service Area must be determined

Not offered in Quest Diagnostics Nichols Institute (IFD) – San Juan Capistrano. Please provide SERVICE AREA INFORMATION to find available tests you can order.

In-home collection may be available in your area for purchase through Quest Mobile.

Test Details

Clinical Significance

Test Resources

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

The CPT codes provided are based on AMA guidance and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

This material contains content from LOINC® (http://loinc.org). The LOINC Table, LOINC Table Core are copyright © 1995-2019, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license.

The tests listed by specialty and category are a select group of tests offered. For a complete list of Quest Diagnostics tests, please adjust the filter options chosen, or refer to our Directory of Services.