Alkaline Phosphatase, Bone Specific

Test Code

29498

CPT Code(s)

84075

Test Code

29498

CPT Code(s)

84075

Not offered in Quest Diagnostics Nichols Institute (IFD) – San Juan Capistrano. Please provide SERVICE AREA INFORMATION to find available tests you can order.

In-home collection may be available in your area for purchase through Quest Mobile.

Clinical Significance

Alkaline Phosphatase, Bone Specific - The bone-specific alkaline phosphatase (BSAP) assay provides a general index of bone formation and a specific index of total osteoblast activity. BSAP and osteocalcin are the most effective markers of bone formation and are particularly useful for monitoring bone formation therapies and antiresorptive therapies.

Test Resources

None found for this test
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Test Details

Methodology

Immunoassay (IA)

Reference Range(s)

Adult Male
18-29 years	8.4-29.3 mcg/L
30-39 years	7.7-21.3 mcg/L
40-49 years	7.0-18.3 mcg/L
50-68 years	7.6-14.9 mcg/L
>68 years	Not established
Adult Female
18-29 years	4.7-17.8 mcg/L
30-39 years	5.3-19.5 mcg/L
40-49 years	5.0-18.8 mcg/L
50-76 years	5.6-29.0 mcg/L
>76 years	Not established
Premenopausal
35-45 years	5.0-18.2 mcg/L

Pediatric	Male (mcg/L)	Female (mcg/L)
2-24 months**	25.4-124.0	25.4-124.0
25 months-5 years	Not established	Not established
6-9 years	41.0-134.6	41.0-134.6
10-13 years	43.8-177.4	24.2-154.2
14-17 years	13.7-128.0	10.5-75.2

**Pediatric data from Int J Biol Markers 1996; 11:159-164.

Alternative Name(s)

OSTASE,Bone Specific Alk Phos,BSAP,Alkaline Phosphatase, skeletal,Alkaline Phosphatase Bones

LOINC® Codes, Performing Laboratory

Service Area must be determined

Methodology

Immunoassay (IA)

Reference Range(s)

Adult Male
18-29 years	8.4-29.3 mcg/L
30-39 years	7.7-21.3 mcg/L
40-49 years	7.0-18.3 mcg/L
50-68 years	7.6-14.9 mcg/L
>68 years	Not established
Adult Female
18-29 years	4.7-17.8 mcg/L
30-39 years	5.3-19.5 mcg/L
40-49 years	5.0-18.8 mcg/L
50-76 years	5.6-29.0 mcg/L
>76 years	Not established
Premenopausal
35-45 years	5.0-18.2 mcg/L

Pediatric	Male (mcg/L)	Female (mcg/L)
2-24 months**	25.4-124.0	25.4-124.0
25 months-5 years	Not established	Not established
6-9 years	41.0-134.6	41.0-134.6
10-13 years	43.8-177.4	24.2-154.2
14-17 years	13.7-128.0	10.5-75.2

**Pediatric data from Int J Biol Markers 1996; 11:159-164.

Alternative Name(s)

OSTASE,Bone Specific Alk Phos,BSAP,Alkaline Phosphatase, skeletal,Alkaline Phosphatase Bones

LOINC® Codes, Performing Laboratory

Service Area must be determined

Preferred Specimen(s)

1 mL serum

Minimum Volume

0.3 mL

Transport Container

Transport tube

Transport Temperature

Room temperature

Specimen Stability

Room temperature: 7 days
Refrigerated: 7 days
Frozen: 21 days

Reject Criteria

Gross hemolysis • Grossly lipemic • Non-serum samples • Grossly icteric

Setup Schedule

Service Area must be determined

Preferred Specimen(s)

1 mL serum

Minimum Volume

0.3 mL

Transport Container

Transport tube

Transport Temperature

Room temperature

Specimen Stability

Room temperature: 7 days
Refrigerated: 7 days
Frozen: 21 days

Reject Criteria

Gross hemolysis • Grossly lipemic • Non-serum samples • Grossly icteric

Setup Schedule

Service Area must be determined

Not offered in Quest Diagnostics Nichols Institute (IFD) – San Juan Capistrano. Please provide SERVICE AREA INFORMATION to find available tests you can order.

In-home collection may be available in your area for purchase through Quest Mobile.

Test Details

Clinical Significance

Test Resources

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

The CPT codes provided are based on AMA guidance and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

This material contains content from LOINC® (http://loinc.org). The LOINC Table, LOINC Table Core are copyright © 1995-2019, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license.

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