Urea Nitrogen (BUN)
Test Code
Clinical Significance
Urea Nitrogen (BUN) - Urea is the principle waste product of protein catabolism. BUN is most commonly measured in the diagnosis and treatment of certain renal and metabolic diseases. Increased BUN concentration may result from increased production of urea due to (1) diet or excessive destruction of cellular proteins as occurs in massive infection and fevers, (2) reduced renal perfusion resulting from dehydration or heart failure, (3) nearly all types of kidney disease, and (4) mechanical obstruction to urine excretion such as is caused by stones, tumors, infection, or stricture. Decreased urea levels are less frequent and occur primarily in advanced liver disease and in overhydration.
Test Resources
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Test Details
Methodology
Reference Range(s)
| Male (mg/dL) |
Female (mg/dL) |
||||
| <1 Month | 4-12 | 3-17 | |||
| 1-11 Months | 2-13 | 4-14 | |||
| 1-3 Years | 3-12 | 3-14 | |||
| 4-19 Years | 7-20 | 7-20 | |||
| ≥20 Years | 7-25 | 7-25 |
Alternative Name(s)
Preferred Specimen(s)
1 mL serum
Alternative Specimen(s)
Sodium heparin (green-top) tube • Lithium heparin (green-top) tube
Minimum Volume
0.5 mL
Transport Container
Serum separator tube (SST)
Transport Temperature
Room temperature
Specimen Stability
- Serum and plasma
- Room temperature: 7 days
- Refrigerated: 5 days
- Frozen: 28 days
Reject Criteria
Anticoagulants other than heparin
Setup Schedule
Room temperature: 7 days
Refrigerated: 5 days
Frozen: 28 days