Estrone
Test Code
23244
82679
Clinical Significance
Estrone - Estrone is primarily derived from metabolism of androstenedione in peripheral tissues, especially adipose tissues. Individuals with obesity have increased conversion of androstenedione to Estrone leading to higher concentrations. In addition, an increase in the ratio of Estrone to Estradiol may be useful in assessing menopause in women.
Test Resources
None found for this test
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Test Details
Methodology
Chromatography/Mass Spectrometry
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Reference Range(s)
| Adult | |
| Male | ≤68 pg/mL |
| Female | |
| Follicular Phase | 10-138 pg/mL |
| Luteal Phase | 16-173 pg/mL |
| Postmenopausal Phase | ≤65 pg/mL |
Pediatric
| Age | Male (pg/mL) | Female (pg/mL) |
| Pre-pubertal (1-9 years) | <10 | ≤34 |
| 10-11 years | ≤12 | ≤72 |
| 12-14 years | ≤28 | ≤75 |
| 15-17 years | ≤64 | ≤188 |
Preferred Specimen(s)
0.5 mL serum collected in a red-top tube (no gel)
Minimum Volume
0.25 mL
Collection Instructions
Specify age and sex on test requisition
Transport Container
Transport tube
Transport Temperature
Refrigerated (cold packs)
Specimen Stability
- Room temperature: 72 hours
Refrigerated: 30 days
Frozen (-20° C): 30 days
Frozen (-70° C): 1 year
Reject Criteria
Gross hemolysis • Lipemia • Serum separator tube (SST)
Setup Schedule
0.5 mL serum collected in a red-top tube (no gel)
0.25 mL
Specify age and sex on test requisition
Transport tube
Refrigerated (cold packs)
Room temperature: 72 hours
Refrigerated: 30 days
Frozen (-20° C): 30 days
Frozen (-70° C): 1 year
Refrigerated: 30 days
Frozen (-20° C): 30 days
Frozen (-70° C): 1 year
Gross hemolysis • Lipemia • Serum separator tube (SST)