ACTH, Plasma
Test Code
Clinical Significance
ACTH, Plasma - Determination of ACTH is useful in differentiating between primary and secondary adrenocortical hypo- and hyperfunctional disorders: Addison's Disease, Cushing's Syndrome, Adrenal Carcinoma, Ectopic ACTH Syndrome, Nodular Hyperplasia.
Test Resources
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Test Details
Methodology
Reference Range(s)
| <3 Years | Not established |
| 3-17 Years | 9-57 pg/mL |
| ≥18 Years | 6-50 pg/mL |
Alternative Name(s)
Preferred Specimen(s)
1.5 mL plasma collected in an EDTA (lavender-top) tube
Alternative Specimen(s)
PPT potassium EDTA (white-top) tube
Minimum Volume
0.5 mL
Collection Instructions
Centrifuge immediately after collection to separate plasma from cells. Transfer plasma to a plastic specimen transport container and mark the specimen type as plasma on the container. Freeze immediately.
ACTH measurement is not recommended for patients who have been administered cosyntropin (ACTH (1-24)) because the results may be falsely elevated or depressed. Reference: Siemens Healthcare Customer Notification IMC20-04.A.US March 25, 2020.
Transport Container
Transport tube
Transport Temperature
Frozen
Specimen Stability
- Room temperature: 16 hours
- Refrigerated: 24 hours
- Frozen: 28 days
Reject Criteria
Received thawed • Received room temperature • Received refrigerated
Setup Schedule
ACTH measurement is not recommended for patients who have been administered cosyntropin (ACTH (1-24)) because the results may be falsely elevated or depressed. Reference: Siemens Healthcare Customer Notification IMC20-04.A.US March 25, 2020.
Refrigerated: 24 hours
Frozen: 28 days