ANA Screen,IFA, with Reflex to Titer and Pattern/Sjogren's Panel 2
Test Code
Clinical Significance
ANA Screen,IFA, with Reflex to Titer and Pattern/Sjogren's Panel 2 -
This panel can be helpful in the diagnosis of Sjogren syndrome by simultaneously testing for antinuclear antibodies (ANAs) with an immunofluorescence assay (IFA), performed on human epithelial type 2 (HEp-2) cells, as well as SSA antibodies, SSB antibodies, rheumatoid factor (RF), thyroid peroxidase (TPO) antibodies, and anti-mitochondrial antibodies (AMAs). For specimens with positive ANA IFA results, reflex testing for ANA titer and pattern is performed. For specimens with positive AMA results, reflex testing for AMA titer is performed.
The laboratory evaluation for individuals with ...
Test Resources
Clinical Focus
Autoimmune Rheumatic and Related DiseasesTest Details
Sjogren's Antibody (SS-A, SS-B)
Rheumatoid Factor
Thyroid Peroxidase Antibody (TPO)
Mitochondrial Antibody with Reflex to Titer
If ANA Screen, IFA is positive, then ANA Titer and Pattern will be performed at an additional charge (CPT code(s): 86039).
If Mitochondrial Antibody Screen is positive, then Mitochondrial Antibody Titer will be performed at an additional charge (CPT code(s): 86381).
Methodology
Reference Range(s)
Alternative Name(s)
Preferred Specimen(s)
1 mL serum collected in each of five separate tubes
Minimum Volume
0.35 mL in each of five separate tubes
Transport Container
Transport tube(s)
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 4 days
- Refrigerated: 7 days
- Frozen: 28 days
Reject Criteria
Gross hemolysis • Grossly lipemic • Grossly icteric • Microbial contamination may interfere
Setup Schedule
Room temperature: 4 days
Refrigerated: 7 days
Frozen: 28 days
Gross hemolysis • Grossly lipemic • Grossly icteric • Microbial contamination may interfere